No 1 (2016)

Cover Page

Full Issue


Optimization of diagnostics and treatment of temporal-mandibular impairments

Tatintsyan L.V.


One of the most common pathologies among lesions dentition is dysfunction of the temporomandibular joint (TMJ). According to literature, 70 to 100% of the population suffer from TMJ pathology. The increasing number of patients with TMJ pathology can be explained by improved diagnosis and increased paraclinical methods, especially by the technical capabilities of medical research. Under our supervision there were 86 patients with various disorders of TMJ dysfunction. Anamnesis data revealed that the patients earlier underwent dental treatment for caries and its complications. Comparison group consisted of 15 people with full dental health and orthognatic bite. One of the assigned tasks was to study the influence of the seal teeth on TMJ. In terms of limitations to seal the teeth of patients in the main group, 26 patients were observed up to 1 year, 32 patients - up to 2 and 28 patients - up to 3 years. Characteristics of sealed teeth of upper and lower jaws were as follows: front - 19 (incisors and cuspids), premolars and molars - 77. Revealed that 85% patients of main group in the first days of the sealing had pain when biting and food intake, and at the 20-30 days - crepitation, clicking and noise in the area of TMJ. Assessment of occlusal relations of the teeth and dentition were determined using wax occlusal and copy paper, with subsequent removal of the casts of both jaws. The models placed into the articulator and received data were recorded in designed “Personal data sheet” of TMJ. Establishing the causes, acute or chronic changes of occlusal relationships (supercontext) should be considered as a fundamental trigger in the pathogenesis of TMJ dysfunction as well as forced position the lower jaw with formation of pathological conditions. In this aspect main role should be given to mistakes and complications during recovery and teeth filling that can cause the dysfunction of TMJ, periodontosis etc. When planning therapeutic interventions in case of TMJ dysfunction clinical and radiographic evaluation, orthopantomography, computed tomography, functional methods of investigation (electronography), and the elimination of the causes leading to its development (occlusal relation of the jaws) are necessary that will greatly enhance the capabilities of diagnosis and treatment.
RUDN Journal of Medicine. 2016;(1):11-18
pages 11-18 views

The distribution of total blood plasma cholesterol among pfur’s students from different climatic-geographic regions

Amaeva A.M., Koshechkin V.A., Kuznetsov V.I.


The concentrations of total cholesterol (CH) in the blood plasma were determined among 246 students of the PFUR. The students were divided into groups according to concentrations of total cholesterol: the “optimal” (CH < 4.4 mmol/l); borderline 4.4 < CH < 5.4 mmol/l); and high (CH > 5.4 mmol/l) for persons under the age of 20 years and young adults older than 20 years, which were accepted as independent risk factors for ischemic heart disease IHD. Borderline values of CH were detected in 19% of students, who require a deeper examination to identify additional risk factors for IHD. Among 5% of the examined students, high concentrations of CH were revealed. This group of students also needs further evaluation and deciding on the need for dietary and pharmacological correction of hypercholesterolemia.
RUDN Journal of Medicine. 2016;(1):19-23
pages 19-23 views

Clinical and electrophysiological predictors of radiofrequency ablation efficacy in patients with atrial fibrillation

Leschinskiy S.P., Ivanov G.G., Tchuyko N.A., Bulanova N.A., Dvornikov V.E.


The article describes prognostic value of clinical and electrophysiological criteria for radiofrequency catheter ablation efficacy in patients with atrial fibrillation. The most important criteria are nonparoxysmal and long persisting forms of atrial fibrillation as well as the age, left ventricular ejection fraction, atrial diameter and volume, underlying cardiac diseases.
RUDN Journal of Medicine. 2016;(1):24-33
pages 24-33 views

Blastocystis spp infections in clinical practice

Tokmalaev A.K., Kogevnikova G.M., Polovinkina N.A., Golub V.P., Barisheva I.V., Prodeus T.V., Smetanina S.V.


Pathogenic properties of Blastocystis spp. - widespread of this protozoan organism remains debatable. Data on clinical observations demonstrating that the manifest forms of invasive Blastocystis spp . can occur from mild diarrhea, dysentery-like, to severe ulcer-necrotizing bowel perforation with complications and poor prognosis. However, one should not exaggerate the pathogenic properties of these protozoa because most infected people are asymptomatic carriers, or have symptoms of diarrhea syndrome of varying severity and duration.
RUDN Journal of Medicine. 2016;(1):34-38
pages 34-38 views

Computed tomography in the diagnosis of diseases of the lungs and pleura

Glagolev N.A., Sakhno Y.P., Blinov V.S.


The review deals with computer-tomographic diagnosis of diseases of bronchopulmonary system and pleura, many of the issues highlighted in the literature not clearly or not covered at all. The introduction into clinical practice of modern methods of diagnosis increases the possibility of detecting disease at an early stage when there is possible to use radical methods of treatment. Despite the high level of modern technologies in the field of visualization of respiratory system, problem early and accurate diagnosis of disease remains highly relevant. Improved results of treatment dependent on the timely and accurate diagnosis. Modern methods of CT is one of the most accurate in radiodiagnostic, allows quickly to obtain significant information about the organs state and tissues of the chest. The work demonstrates the potential of CT in clinical decision making when observing patients with diseases of bronchopulmonary system and pleura.
RUDN Journal of Medicine. 2016;(1):39-53
pages 39-53 views

Nutritional status disordes and comorbidities in children

Gudkov R.A., Dmitriev A.V., Fedina N.V.


Several comorbid measures demonstrates the predictive ability for children's health. The association of body mass index (BMI) categories with comorbidities studied in 317 children of 7-15 year old. Body mass index and presence of chronic condition were assessed. Comorbidity index was estimated in subgroup of children with BMI ±1SD, ±2SD, ±3SD. Children with normal weight had comorbidity index of 3.2. Increase or decrease of BMI is associated with rise of comorbidity index. Obesity as well as protein-energy malnutrition increases comorbidity index more than to 4 in children. Impaired nutritional status can be considered as an independent risk factor for concomitant pathology in children. Increase of comorbidity in obesity and underweight is predominantly nonspecific in nature. Obesity in children is characterized by the formation of a specific set of diseases, which together can be considered as a single characteristic polypathy.
RUDN Journal of Medicine. 2016;(1):54-60
pages 54-60 views

Hyperhomocysteinemia and its correction in posttrombotic syndrome of the lower limbs

Kalinin R.E., Suchkov I.A., Rudakova I.N., Nikiforova L.V.


The article is about hyperhomocysteinemia which retards recanalization processes after deep vein thrombosis and leads to the lower extremities post-thrombotic syndrome. Levels of blood homocysteine were determined at admission, after 1 and 3 months after the acute thrombosis of the deep veins of the lower extremities. Increased levels of homocysteine were revealed. Maximum concentration of homocysteine was 31.6 mmol/l, which corresponds to moderate hyperhomocysteinemia. In patients receiving anticoagulants for 3 months the level of homocysteine slightly decreased. Prescription of vitamins B6, B9, B12 allows significantly decrease the homocysteine levels, improve health outcomes, reduce the number of patients with class C3-4.
RUDN Journal of Medicine. 2016;(1):61-67
pages 61-67 views

Early diagnosis of the rotator cuff damage

Kondirev N.M., Kopenkin S.S., Scoroglyadov A.V.


We have analyzed the causes of late admission of the patients with rotator cuff injuries (RCI). 29.2% of the patients didn’t seek medical attention in the timely manner, and the diagnosis was made incorrectly in 27.5% of cases. Based on 120 cases, a diagnostic algorithm for the rotator cuff injuries had been developed allowing to put a correct diagnosis in the early stages.
RUDN Journal of Medicine. 2016;(1):68-76
pages 68-76 views

Diagnostic algorithm of snore and sleep apnea in pations with nasal and pharyngeal obstruction

Panin V.I., Pikhtileva N.A.


The article presents diagnostic algorithm of snore and sleep apnea in ENT practice. Investigation of 81 patients with signs of nasal and pharyngeal obstruction revealed that 29 of them had obstructive sleep apnoea, 52 - primary snore without apnoea. A survey on diagnostic criteria of the International Classification of Sleep Disorders (ICSD) with visual-analogous scale was used. The study showed low concern of patients about the problem of snoring and obstructive sleep apnoea.
RUDN Journal of Medicine. 2016;(1):77-81
pages 77-81 views

Dynamics of electroneuromyography in postoperative period after mandible fractures

Ushnitskiy I.D., Terent’eva Z.V., Kononova E.E., Golokova E.A., D'yachkovskaya M.P.


Nowadays there is increase in the frequency of mandibular fractures, as well as the weighting of the nature of the fracture. At the same time, there is a tendency to growth of fractures of the articular processes of the mandible and comminuted fractures. With a wide access to intralesional mandibular extraoral fixation occurs re-tension and damage the edge branch of the facial nerve. Conducted functional assessment of efficiency of application of “Heparin” in complex treatment of mandibular fractures. 84 patients with fractures in the angle and the articular process of the mandible, as well as comminuted fractures underwent osteosynthesis. For the study, two groups were formed: with standard treatment and with the use of “Epsorin”. Electroneuromyography of facial nerve branches was performed in 2, 7 and 14 days after surgery. The data confirm recovery of demyelinated nerve fibers and axonal damage in postoperative wound in the main group compared with the control. As a result this medication can be used in treatment of traumatic injuries of mandible as an alternative means.
RUDN Journal of Medicine. 2016;(1):82-87
pages 82-87 views

Splanchnic hemomicrocirculation in abdominal surgery

Lukoyanychev E.E., Ryabkov M.G., Mironov A.A., Rotkov A.I.


Splanchnic blood circulation in patients with emergency surgical diseases and abdominal injuries is an integral indicator of functional disorders and a prognostic index of multiple organ failure development. The purpose of the research was to study abdominal membrane splanchnic hemomicrocirculation in the abdominal surgery conditions. As a result, specifics of abdominal hemomicrocirculation disruptions during a surgical intervention was revealed. It was established that the “open abdomen” method is not recommended for treatment of intra-abdominal hypertension and shall be replaced with other methods of decompressive closure of the abdominal cavity.
RUDN Journal of Medicine. 2016;(1):88-94
pages 88-94 views

Monitoring of regional indicators of morbidity, mortality and lethality Orendurg region population as result of vascular diseases

Aprelev V.E., Aprelev E.V., Markelova E.N., Kalinina E.A.


The paper analyzes the morbidity, mortality in the adult population of the Orenburg region due to cardiovascular diseases. Noticed increase in overall incidence of diseases characterized by high blood pressure. Marked increase in overall incidence of diseases characterized by high blood pressure. In 2013, the proportion of cardiovascular disease accounted for 56.3% of all causes of mortality. In the structure of primary morbidity of diseases of the circulatory system the proportion of cerebrovascular diseases was 25.1%, and in the structure of overall morbidity - 20.9%. Among the cerebrovascular diseases cerebral infarction (ischemic stroke) - 91,5% - was leading. Average annual rate of hospitalization due to cerebrovascular diseases in the adult population of the Orenburg region was 8,6 per 1,000 population, rate of mortality - 11.6%, and the leading cause of mortality was cerebral infarction (62.8%).
RUDN Journal of Medicine. 2016;(1):95-101
pages 95-101 views

Prospects of improving staff training system for the medical industry

Breusov A.V., Otstavnov S.S.


The authors of the article analyzed the status, problems and ways of improving the training system for the medical industry. Based on his own experience, analysis of the existing system of training in the field of biomedical engineering, evaluation of health system needs for specialists in the repair and maintenance of medical equipment identified the main problems in the training of specialists in this profile and recommendations for their improvement, taking into account the needs of industry.
RUDN Journal of Medicine. 2016;(1):102-107
pages 102-107 views

Awareness of patients of dermatovenerological institutions for prevention and treatment of syphilis

Volkova S.B.


The article presents the results of a survey of patients of dermatovenerological institutions of Moscow. Analyzes their views on syphilis as a medical-social problem. The characteristic views of respondents about prevention, possible ways of infection and the relationship to the self-treatment of syphilitic infection are described. Provides data about the negative consequences of untreated syphilis in the opinion of the respondents.
RUDN Journal of Medicine. 2016;(1):108-113
pages 108-113 views

Analysis of the range of medications for treatment of psoriasis

Kaverina E.V.


The aim of the study was to analyze the range of medications registered in the Russian Federation for reatment of psoriasis. We have studied the State Register of drugs of Russian Federation and the treatment standards of patients with psoriasis, published on the website of the Ministry of Health of the Russian Federation.
RUDN Journal of Medicine. 2016;(1):114-117
pages 114-117 views

Analysis doctor's opinion about the quality of medical and pharmaceutical care of patients with chronic skin diseases

Kaverina E.V., Fomina A.V.


The article is devoted to studying the views of doctors about the current state of the treatment of patients with chronic skin diseases such as psoriasis, eczema and atopic dermatitis. To determine the current situation and to improve the quality of medical and medicinal care of patients with chronic skin diseases dermatologists, internists, general practitioners, allergists were surveyed in the Tula region in order to give an expert assessment of the situation.
RUDN Journal of Medicine. 2016;(1):118-122
pages 118-122 views

Antimicrobial preservatives medicines for children

Kolosova L.V., Gunar O.V.


The article describes the use of antimicrobial preservatives in medicines for children Authors analyzed domestic and foreign regulatory documents, which establish requirements for the quality of mdications and identified the main dosage forms with preservatives. Current data about the range of antimicrobial preservatives, containing in the various dosage forms is presented.
RUDN Journal of Medicine. 2016;(1):123-128
pages 123-128 views

The prevalence of some lifestyle risk factors among rural adolescents with chronic gastroenterological pathology

Pozdnyakova M.A., Spiridonova E.B.


Emergence and development of gastroenterological pathology in teenagers are influenced by a number of factors, among which the image and living conditions play an important role. The article is devoted to studying of these factors among rural teenagers. The study revealed a low motivation for preservation of health, the high incidence of harmful habits among teenagers. The family plays a key role in the formation of adolescent healthy lifestyle.
RUDN Journal of Medicine. 2016;(1):129-134
pages 129-134 views

Modern trends in perinatal and neonatal mortality in the Moscow region

Konovalov O.E., Haritonov A.K.


The dynamics of perinatal and neonatal mortality in the Moscow region in comparison with indicators of the Central Federal District and the Russian Federation as a whole is analyzed in the article. The ratio of stillbirth and early neonatal mortality is given in the article. Characteristic of the causes of death in newborns considering birthweight are given.
RUDN Journal of Medicine. 2016;(1):135-140
pages 135-140 views

Follow-up of oncological patients in outpatient department

Potapov S.O., Sharafutdinov M.A., Sultanov R.Z.


The article presents the data of analysis of the organization of medical care for patients with oncological diseases in outpatient depertment. The type and scope of primary health care? Including at home, by an oncologist as well as by physicians, had been defined. The study enrolled 984 patients (av. age 69,69 ± 0.4 years), which were followed up by oncologist in the primary oncological consulting room. 35,1% of patients were men of 68.6 ± 0,7 years, 64.9% - women of 70,2 ± 0.4 years. Patients visited their doctors about 15 times during a year, including 4,5 visits to therapeutist, 3,7 - to surgeon, 3,2 - to neurologist, etc. The reasons for patients references to the doctors were mostly related diseases The oncological patients visited an oncologist 3,1 times a year, the highest number of visits made by patients with the disease of the prostate and breast. The reason of these visits was monitoring the patient's health status, medication and others. An oncologist paid 3,9 visits to patients with III-IV stage of the disease for palliative care. Of the 48.0% of the patients enjoyed preferential drug provision, being in the list of federal benefit recipients. Within a month, they had received medications of 2,768,800 rubles, the average per patient - 6478 rubles
RUDN Journal of Medicine. 2016;(1):141-149
pages 141-149 views

Medico-social characteristic of health-behavior of the adult population of megapolis

Serov D.V.


The article presents the results of a survey of 452 adult patients who received outpatient treatment in medical institutions of Moscow. Considered the aspects of evaluation of their own health based on the presence of chronic disease. The characteristics of medical activity, including the frequency and timing of seeking medical help for the diseases are discussed. Analyzed sanogenic (healthful) activity and the prevalence of harmful habits among the studied contingent.
RUDN Journal of Medicine. 2016;(1):150-157
pages 150-157 views

Cooperation of gcc countries in the health field

Al-Washai Mohammed Abdo Ahmed -.


The article analyzes the state of health systems in the Arab countries of the Persian Gulf, as well as factors affecting this area. Particular attention is paid to the Arab states cooperation in the protection of public health, improving medical services quality, infrastructure, resource and technology base and promotion of preventive measures in the format of the GCC.
RUDN Journal of Medicine. 2016;(1):158-160
pages 158-160 views

CT-scan diagnostics of emphysematous pyelonephritis in patients with diabetes

Rudnev A.O., Maksim M.N., Kovylina N.M.


Presented clinical case in the article confirms the high diagnostic value of computed tomography in the detection of emphysematous pyelonephritis on the example of a patient with diabetes mellitus.
RUDN Journal of Medicine. 2016;(1):161-165
pages 161-165 views

Goodpasture’s syndrome in 17-year-old patient

Ovsyannikov D.Y., Volkov M.Y., Glazyrina A.A., Marchenkov Y.V., Gitinov S.A., Rogatkin P.S., Koltunov I.Y.


Goodpasture’s syndrome (GS) is a severe autoimmune disease, which is characterized by kidney and lung affection. Antibodies to glomerular basal membrane (AGBM) are considered to be a specific marker. We present a literature review and a clinical case of GS with typical clinical presentation and low effectiveness of glucocorticosteroid treatment in 17-year-old patient. The disease was characterized by the AGBM disappearance from peripheral blood, positive test for cryoglobulins and improvement of patient condition during therapy with rituximab.
RUDN Journal of Medicine. 2016;(1):166-172
pages 166-172 views

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RUDN Journal of Medicine. 2016;(1):173-179
pages 173-179 views

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