Goodpasture’s syndrome in 17-year-old patient

D Yu Ovsyannikov; Овсянников Дмитрий Юрьевич; M Yu Volkov; Волков Михаил Юрьевич; A A Glazyrina; Глазырина Анастасия Александровна; Ya V Marchenkov; Марченков Ярослав Владимирович; Sh A Gitinov; Гитинов Шамиль A; P S Rogatkin; Рогаткин Петр Сергеевич; I Ye Koltunov; Колтунов Игорь Ефимович

Goodpasture’s syndrome in 17-year-old patient

Authors: Ovsyannikov DY.¹, Volkov MY.¹, Glazyrina AA², Marchenkov Y.V³, Gitinov S.A¹, Rogatkin PS², Koltunov IY.¹
Affiliations:
1. Peoples Friendship University of Russia
2. Morozov Children Clinical City Hospital
3. CDC MEDSI
Issue: No 1 (2016)
Pages: 166-172
Section: Articles
URL: https://journals.rudn.ru/medicine/article/view/3756
ID: 3756

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Abstract

Goodpasture’s syndrome (GS) is a severe autoimmune disease, which is characterized by kidney and lung affection. Antibodies to glomerular basal membrane (AGBM) are considered to be a specific marker. We present a literature review and a clinical case of GS with typical clinical presentation and low effectiveness of glucocorticosteroid treatment in 17-year-old patient. The disease was characterized by the AGBM disappearance from peripheral blood, positive test for cryoglobulins and improvement of patient condition during therapy with rituximab.

Keywords

Goodpasture’s syndrome, anti-GBM disease, pulmonary-renal syndrome, cryoglobulins, children

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Goodpasture’s syndrome in 17-year-old patient

Full Text

Abstract

Keywords

About the authors

References

Supplementary files