No 1 (2011)


Characteristics of cardiac function state in an acute experimental hemodynamic overload of the left ventricle

Blagonravov M.L.


On animal model of an acute hemodynamic overload of the left ventricle (LV) caused by the artificial aortic stenosis, some characteristics of left and right ventricular contractive activity and diastolic function were studied. It was found that a sudden increase in afterload leads to a significant reduction of contractive activity and potential working capacity of both ventricles. LV also suffers from diastolic dysfunction.
RUDN Journal of Medicine. 2011;(1):7-11
pages 7-11 views

Features of blood microcirculation in the skin at children

Gurova O.A., Kozlov V.I.


The characteristics of a skin blood microcirculation by method of laser Doppler flowmetry (LDF) in 70 children at the age from 4 till 7 years are studied. During this period of life, gradual decrease in intensity of blood microcirculation in the skin is observed. For surveyed children three types of microcirculation are characteristic: mesohaemic, hypohaemic and hiperhaemic. Mesohaemic type of microcirculation (51,4% of children) prevails with balanced sympathetic and parasympathetic regulatory influences.
RUDN Journal of Medicine. 2011;(1):12-16
pages 12-16 views

Repeated multi intervention on aorta and arteries of the lower extremities

Mizaushev B.A., Aslanov A.D., Taukenova l.I., Ishaq L.N., Havpachev A.S., Edigov A.T.


The article presents the results of the survey and treatment of 108 patients admitted with the clinical relapse of chronic critical ischemia of lower extremities that arose at different times after the primary reconstructive operations. In a special survey of patients revealed that 40.7% of cases there was an objective reason for the development of postoperative complications and recurrence of critical ischemia. All patients were operated on again in the light of the identified causes, preventive measures taken by the development of complications. Obtained good results - in 78,7% of cases arterial blood flow restored. The optimal method of repeated reconstructive interventions depending on the cause of relapse of chronic critical limb ischemia, developed indications and methods of combined treatment with the development of postoperative complications after the primary reconstructive interventions. It performs the following operations: resection of abdominal aortic aneurysm, aorto-bifemoralnoe prosthetics, multilevel bypass limb, femoral-tibial artery bypass technique «in situ», thrombectomy and autogenous vein anastomosis and profundoplasty.
RUDN Journal of Medicine. 2011;(1):17-23
pages 17-23 views

Clinical efficiency of panavir in therapy of chronicle papillomavirus infections of cervix uteri

Kovchur P.I., Bahlaev I.E.


This research is devoted to determination of the clinical efficacy of Panavir in the combined therapy of the uterine cervix diseases associated with human papillomavirus (HPV). The article presents data of the complex examination of 59 patients. Patients with diagnosed 16th, 18th, 31st, 33rd types of HPV underwent destructive methods of treatment of the cervix followed by Panavir. The efficacy of Panavir was estimated by PCR in 3, 6 and 12 months from the beginning of treatment and it was 84,7%. Antiviral therapy permits to prevent recurrence of papillomavirus infection of the cervix uteri.
RUDN Journal of Medicine. 2011;(1):24-28
pages 24-28 views

Our experience of lymphotropic antibiotic therapy during post-operational period of patients who underwent surgery of major joints. research of lipid peroxidation processes and anti-oxidant protection system in red-cell membrane

Zagorodnyi N.V., Azizov M.J., Shakirov H.H.


Aim: to study lymphotropic antibiotics therapy for prevention of postoperative inflammatory complications after the surgery on the major joints. Two groups of patients were involved in this study. In the first group, prophylaxis of infection has been carried out according to traditional scheme including intravenous injections of antibiotics, whereas in the second group antibiotic therapy - through lymphotropic injections. Blood (erythrocytes) analyses had been doing in dynamics - prior to treatment, on the 3rd and 10th days after the operation. Strength of content of malon dialdehyde (MD) and systemic lipids have been measured in the red-cell membrane. Condition of antioxidant protection (AOP) has been evaluated according to the activity of superoxide dismutase (SD), catalase, glutathione peroxidase (GP) and glutathione reductase (GSR) enzymes. It is established that lymphotropic antiobiotic therapy allows to decrease in a greater degree the destructive effect of lipids peroxidation processes, to increase potential capacity of AOP enzymes, to restore barrier-filtration and transportation-drainage function of lymphatic vessels that favorably effects on the processes of reparation and physiological regeneration of damaged tissues.
RUDN Journal of Medicine. 2011;(1):29-33
pages 29-33 views

Early menopause influence on the development of metabolic syndrome

Kovalenko L.V., Belotserkovtseva L.D., Korneeva E.V., Sisanok O.J.


Deficiency of sex hormones at the age of 40 years promotes emotional, vegetative-vascular and metabolic manifestations of a few years prior to the physiological age of menopause. Investigation of 180 women with early menopause of different genesis revealed that 48,3% of them have had insulin resistance, which can be regarded as the main factor of development of metabolic syndrome.
RUDN Journal of Medicine. 2011;(1):34-38
pages 34-38 views

The peculiarities of parametrical changes of free radical oxidation, endogenic intoxication and liver condition at treatment of dysfunctional uterine bleeding with progesteron and utrogestan

Saleh R.H.


Peculiarities of changes in free radical oxidation, endogenic intoxication and functional condition of liver were studied in patients with dysfunctional uterine bleeding at treatment with Progesteron and Utrogestan. It is shown that the level of free radical oxidation increases and the activity of antioxidant protection decreases on the background of elevated endogenic intoxication. It is accompanied by decrease of the liver protein synthetical function and increase activity of tracer enzymes - cytolyses markers. Progesteron increases endogenic intoxication and hypoalbuminemia on the background of increased activity of peroxide lipids oxidation in case of initial liver's function disorder. Utrogestan increases hypoalbuminemia on the background of increased activity of tracer enzymes along with decreased intensivity of peroxide lipids oxidation and preservation of depression of antioxidatic protection and endointoxication. These changes are necessary for considering at treatment planning.
RUDN Journal of Medicine. 2011;(1):39-42
pages 39-42 views

Social and hygienic characteristics of gynаecologist, working in women`s consultations and hospitals of Saint-Petersburg

Komlichenko E.V.


In the article data about pattern of gynаecologists, working in the health care facilities of Saint-Petersburg is presented. Sociological interview was the main method of research. Particularly, data about age-sex pattern of doctors, their qualification level, self-estimation of theirs health are described. Doctor's satisfaction of their job and reasons to be unpleased of it are also analyzed. Doctor's self-estimation of their knowledge level in different questions, concerning their profession is discussed in the article.
RUDN Journal of Medicine. 2011;(1):43-47
pages 43-47 views

Actual problems in out-patient stomatologic practice at rendering assistance by the cardiological and cardiovascular patient

Velichko E.V., Gunko V.I.


The review deals with a problem of rational treatment of cardiovascular patients. There is increased percent of surviving patients after heart operations due to improvement of surgical technique and who require the subsequent dental treatment. To the present day, there are no universal approaches to investigation and management of such patients for outpatient dental practice.
RUDN Journal of Medicine. 2011;(1):48-52
pages 48-52 views

Individual-specific selection of the antihomotoxic therapy based on the interferon response of leukocytes (IRL)

Chernogortsev A.V., Novikova E.B.


Conducted for the first time studies of value of the interferon response of leukocytes (IRL) for the individual-specific immuno-modulating homeopathic therapy in the patients with chronic bronchopulmonary and digestive systems disorders are presented. We analyzed the antihomotoxic homeopathic medicine-induced production of interferon in blood cells in vitro.
RUDN Journal of Medicine. 2011;(1):53-57
pages 53-57 views

The comparative characteristic of influence separate statin on rheological properties erythrocyre at sick of the arterial hypertension with dyslipidemia

Medvedev I.N., Skorjatina I.А.


The purpose - comparative investigation of influence of inhibitors hydroxy-methyllglutaril co-enzyme A-reductase - Fluvastatin, Lovastatin and Simvastatin on rheological properties of erythrocytes in patients with arterial hypertension and dyslipidemia. The total number of enrolled patients was 95 and all of them had arterial hypertension 1-2 degrees, risk 3 and dyslipidemia II type (recommendation VNOK, 2007). The average age of patients was 52,4 ± 2,6 yrs. The control group included 26 healthy people of similar age. Patients have been divided into 3 comparable, homogeneous groups according to administration either Fluvastatin or Lovastatin or Simvastatin for 12 months in each group. Administration of Fluvastatin and Lovastatin in patients with arterial hypertension with dyslipidemia within 1 year is capable to reduce activity lipid oxidations of lipids in erythrocyte membranes, its deformation changes and aggregation activity whereas the therapy by Simvastatin allows the erythrocyte activity to reach the values in control group.
RUDN Journal of Medicine. 2011;(1):58-65
pages 58-65 views

The screening of the compounds with antiaggregation and proaggregation activity among xantine

Kamilov F.С., Timirkhanova G.A., Samorodov А.V., Khaliullin F.A., Gubaeva R.A.


Biological activity of first synthesized 8 xantine derivatives has been studied. Differences in impact of the compounds on blood coagulability have been shown. Obtained active derivates prove the perspectives of further investigations of bioactive substances.
RUDN Journal of Medicine. 2011;(1):66-69
pages 66-69 views

Experimental substantiation of alcoholic extracts technology from the scrophulariaceae family plants

Shramm N.I., Babiyan L.K., Petrichenko V.M.


The optimum preparation conditions (including the degree of the raw materials grinding, ethanol concentration, infusion time, preparation technique) of alcoholic extracts from Euphrasia, Melampyrum, Verbascum herbs providing the maximum yield of biologically active substances have been determined. The technology of dry and liquid Euphrasia extracts, liquid Melampyrum extract, dry Verbascum extract has been developed.
RUDN Journal of Medicine. 2011;(1):70-72
pages 70-72 views

The role of the reinhold voll's electroacupunctural diagnostics in rehabilitation of the patients with lung disoders

Novikova E.B., Chernogortsev A.V.


This study evaluates for the first time the role of Reinhold Voll's electroacupunctural diagnostics as a screening method for in-depth diagnostics, treatment and rehabilitation in a high-risk lung disease group. We founded correlations between the electrocutaneous conductivity measures in the meridian lung system and the results of the clinico-instrumental diagnostics of lung diseases in both «normal» and «high-risk» groups consequently.
RUDN Journal of Medicine. 2011;(1):73-77
pages 73-77 views

Uapplying of point system in evaluation of some gerontological change in the eye of ophthalmoligical profile patients

Frolov M.A., Gonchar P.А., Boryanova N.V., Radish B.B.


In this study we offer the special point system for evaluation of some changes of the eye in people of different age. Using this special point system, we examined 105 patients from 35 to 91 years old who were divided into 4 groups according to their age. The results showed different sums of points in the groups: I group - the mean sum of points was 36 points; II group -48 points; III group - 85 points; IV group - 97 points consequently. Degenerative changes of the eye's structures were proved by digital instrumental methods.
RUDN Journal of Medicine. 2011;(1):78-81
pages 78-81 views

Mental disorders in distant postoperation perioud of radiofrequency ablation operation

Artemieva M.S., Alexandrova M.R., Yurovskaya I.I.


Article describes a clinical case of cardiophobia and panic attacks manifestation in patient with AV reciprocal tachycardia who underwent radiofrequency ablation with pacemaker explantation.
RUDN Journal of Medicine. 2011;(1):82-86
pages 82-86 views

Peculiarities of workers nervous system properties of different professional groups in extreme activities

Rodygina Y.K., Deryagina L.E.


369 employees of extreme services (males) aged from 18 to 49 years were explored by Y. Strelau's method to assess the properties of higher nervous activity. According to the professional activity, three groups of people are identified whose work is related to the daily extreme conditions. Extended study of peculiarities of worker's nervous system properties of different professional groups in extreme activities was carry out in a sample of employees of the Ministry of Internal Affairs. It is revealed that professional groups carrying out activities in stressful working condition differed high indicators of force of nervous processes and their mobility. Specific parameters of nervous system are determined for different professional groups. The dynamics of nervous system during extreme professional service is revealed.
RUDN Journal of Medicine. 2011;(1):87-90
pages 87-90 views

Reference of N.G. Petrova's е.а. article «about problems of standartization in public health services»

Petrova N.G., Malinin A.N., Komlichenko Е.V., Zubareva T.M., Ivanov A.V., Sheveleva T.S.


Article is devoted to the problems of providing qualified medical health care to population. By the author`s opinion, the solving of this problem is impossible without wide-spread introducing of system of standards in public health service. Standardizing must be spread in all quality components: structural, technological and resulting. Authors prove imperfections of existing technological standards on the example of gynaecological service. Other standards are too old, or are not still worked out until nowadays. Working out of standards - is a priority aim, which can increase public health services efficiency.
RUDN Journal of Medicine. 2011;(1):91-94
pages 91-94 views

Diagnostic opportunities of dispersion mapping in estimation of infringement coronary blood-flow and electrophysiological properties of myocardium at patients with coronary artery disease

Ahmed Elgaili Ahmed -., Dvornikov V.E., Aleksandrova M.R., Kuznetsova S.Y., Ivanov G.G.


Dispersive mapping is a new method of the diagnostic electrocardiogram. In the basis of this method is the analysis of low amplitude fluctuations of ECG-signal, existing in norm and pathology. Results of the lead researches have allowed to designate a range of changes the parameters of a dispersion for healthy persons at loading and patients with ACS.
RUDN Journal of Medicine. 2011;(1):95-98
pages 95-98 views

Elaboration of techniques for analysis of antioxidant preparation «Vitaox»

Prostolupova A.V., Vdovina G.P., Rozhkova N.Y., Yarygina T.I.


Techniques of analysis of new antioxidant preparation «Vitaox» which contains dihydroquercetin and ascorbinic acid have been developed. It has been proposed to determine dihydroquercetin by method of high-performance liquid chromatography and an ascorbinic acid by method of titrimetry. Results of study of validation parameters: specificity, repeatability, precision, accuracy or trueness, linearity and system suitability have been presented.
RUDN Journal of Medicine. 2011;(1):99-102
pages 99-102 views

Modern problems of male mortality (on an example of the Republic of Bashkortostan)

Fattakhov I.A.


The article presents the data on death rate of rural and urban male population in the Republic of Bashkortostan in the 2008. The standardized indicators demonstrate that death rates from cancer, diseases of blood circulation and respiratory systems were higher among urban men. On the contrary, among rural men the mortality from traumas is considerably above.
RUDN Journal of Medicine. 2011;(1):103-105
pages 103-105 views

The development and approbation of educational-methodical informational complex «Cosmetics» for elective course with elements of distance education

Sattarova O.E., Babian L.К., Shramm N.I., Yarygina T.I.


The educational-methodical informational complex on pharmaceutical technology «Cosmetics» for pharmaceutical students was elaborated. The elective course with elements of distance education was carried out. The results of the experiment on conducting an elective course are described.
RUDN Journal of Medicine. 2011;(1):106-108
pages 106-108 views

Demographic indicators of the health state of population in Ufa

Sharafutdinova M.J.


Authors analyzed indicators of mortality in the population of Ufa city from 2002 to 2008. A mortality rate for all causes of death has decreased for both men and women, mainly from the external causes and disease of the respiratory system. An increase In the certain age groups: among men aged of 25-29, 30-34 and 65-69 years and among women of 30-34, 35-39 and 45-49 years this rate was increased.
RUDN Journal of Medicine. 2011;(1):109-111
pages 109-111 views

Allele's variants of gene MTHFR and remodelling the myocardium of the left ventricle at patients on the hemodialysis

Kharlamova U.V., Ilyichev O.E.


The article shows the statistically authentic association between Т allele gene MTHFR and development of a concentric hypertrophy left ventricular in patients on the hemodialysis.
RUDN Journal of Medicine. 2011;(1):112-114
pages 112-114 views

Modern tendencies of reproductive process and the organization of service of obstetric aid in republics of the North Caucasus

Badoeva Z.A., Salbieva S.Z., Yachyaeva Z.I., Djioeva I.A., Gogichaeva M.T.


The main feature of reproductive processes in republics of the North Caucasus is the increasing of birth rate. However adverse dynamics of perinatal losses does not allow to estimate unequivocally change, as positive. Despite of some positive tendencies, it is necessary to optimize the maternity obstetric service by creation of perinatal centers in each republic and improvement of quality of medical aid to the female population.
RUDN Journal of Medicine. 2011;(1):115-118
pages 115-118 views

Phytopreparation - inhibitor of bacterial catalase in therapy of patients with flegmons

Мustafaev М.S., Kharaeva Z.F., Gendugova О.М.


The phytopreparation on the papaya base may be regarded as indirect antibiotic, which inhibits the staphylococcus catalase. The estimation of clinical effectiveness of therapy by BioReks demonstrates that such therapy leads to the faster arresting of main inflammatory symptoms and complete healing of wound.
RUDN Journal of Medicine. 2011;(1):119-121
pages 119-121 views

The actuality of the problem and main forms of the organization of medical and social care to the old patients and handicapped persons

Epelman B.V.


The growth of the old people's population is the reason for the increasing of requirement for the medical and social care and the financial resources. So, it is necessary to find a new organizational forms of rendering of such care. Author analyses the structure of medical and social care to the old people and its new forms as exemplified by one district of Saint-Petersburg. Special attention is paid to such forms, which permit to integrate the medical and the social services (the geriatric social - rehabilitation department, multidisciplinary team for the patients with strike and so on).
RUDN Journal of Medicine. 2011;(1):122-125
pages 122-125 views

Characteristics of hemodinamic and vegetative parameters in teenagers with adiposity

Larina N.G.


The parameters of central hemodynamics and vegetative reactions to cold stress in teenagers with adiposity and the vegetative dysfunction (hypertonic type) and in teenagers with normal body mass index (BMI) and vegetative dysfunction (hypertonic type) are investigated. It is revealed Desadaptation of the vegetative and the hemodinamic maintenance of stress in teenagers with adiposity and significant sa of development parasympathetic reaction with high level of anxiety despite of BMI. The big frequency of development of sympathetic reaction at girls with adiposity and vegetative dysfunction on hypertonic type is revealed.
RUDN Journal of Medicine. 2011;(1):126-128
pages 126-128 views

Sociological interpretation and substantiation of success of doctor's professional innovative activity

Shurupova R.V.


The author of the article considers sociological interpretation of success of doctor's professional innovative activity, proves necessity of comprehension of socio-cultural problems of innovations, on the basis of advanced achievements of sociology of medicine, strategy of innovative development of the country.
RUDN Journal of Medicine. 2011;(1):129-135
pages 129-135 views

Development of illustrative materials on pharmaceutical chemistry

Sattarova O.E., Yarygina T.I.


The illustrative materials on pharmaceutical chemistry for the full-time students were developed. Illustrations were used while conducting distance courses on pharmaceutical chemistry. The implementing of such materials provides visual expression of study, promotes student's cognitive activity and contributes to the better understanding of pharmaceutical chemistry.
RUDN Journal of Medicine. 2011;(1):136-139
pages 136-139 views

Testing of hydroxyapatite nanocrystals and epidermal growth factor for healing of skin wounds in rats with an immunodeficiency

Topolnitsky О.Z., Sergeev S.А.


Experiment on 30 rats with the secondary immunodeficiency is conducted. On the dorsum of the back identical wounds were simulated. Rats were divided on groups, in a control group (a suspension was not used) and on 2 experimental groups (a suspension was used with the different concentrations of EGF). It was revealed that preparation of EGF + hydroxyapatite nanocrystals also has the ability to stimulate regeneration in case of immunodeficiency.
RUDN Journal of Medicine. 2011;(1):140-142
pages 140-142 views

Medico-socio-psychological technologies of patient support during ophthalmosurgery

Kukanova N.N., Plyakov B.A., Mushnikov D.L.


The article is devoted to improvement of the health care quality technologies. The authors offer a new classification of medico-organizational technologies of patient support in the health facilities, and also present the results of investigation, reflecting the experience of integration of these technologies into the practice of a non-state health facility - the Ivanovo Interregional Ophthalmo-surgical clinic.
RUDN Journal of Medicine. 2011;(1):143-147
pages 143-147 views

Social portrait of a patient of the therapeutical department

Solodoukhina D.P.


The article presents the results of investigation of the social characteristics of patients in therapeutical department of the municipal and central district hospitals. Influence of social status on appropriateness of hospitalization and suitable alternatives for in-patient care have been investigated.
RUDN Journal of Medicine. 2011;(1):148-151
pages 148-151 views

Low level laser therapy in the complex therapy of pelvic organs prolapse

Nechaykin A.S., Peshev L.P., Abramova S.V., Islamova M.N.


86 women with pelvic organs prolapse were examined, including 51 women who have undergone low level laser therapy (LLLT) before and after surgery. It was revealed that LLLT accelerates reparative processes, reduces the expectation of inflammatory complications and leads to increasing of recoveries by 15,0% and reduces period of treatment by 5 days.
RUDN Journal of Medicine. 2011;(1):152-154
pages 152-154 views

Disorders in membraneous reactions related to lipid peroxidation in women with phlebothrombosis of the lower extremities

Schulatkina A.V., Peshev L.P.


The membraneous reactions of lipid peroxidation in women with phlebothrombosis of the lower extremities were studied. Increased level of malonic dialdehyde - product of POL, in erythrocytes and decreasing of enzymatic catalase activity in blood were revealed. It was supposed that one of the main causes of phlebothrombosis are destabilization and destruction of erythrocyte membranes due to disorders of POL.
RUDN Journal of Medicine. 2011;(1):155-156
pages 155-156 views

Modulation in cardiodynamics in women - operators of personal computers

Tumaeva Y.A., Peshev L.P.


Analysis of modulations in cardiodynamics of 22 women - PC operators was performed by «Varicard» automated system. It was revealed that computer's electromagnetic emission may decrease the myocardial pumping ability and increase the heart rate.
RUDN Journal of Medicine. 2011;(1):157-158
pages 157-158 views

Dispersion mapping in donozologic diagnostics

Kuznetcova S.Y., Escherekoeva E.B., Dvornikov V.E., Aleksandrova M.R., Ivanov G.G.


Work is dedicated to description of the possibilities of the new method - dispersion mapping.
RUDN Journal of Medicine. 2011;(1):159-161
pages 159-161 views

Clinico-immunological effectiveness of immunotherapy in patients with respiratory syncytial virus infection

Klimova Y.A., Tokmalaev A.K., Balmasova I.P.


We studied 44 patients with different complications of respiratory syncytial virus infection (bronchitis, acute tonsillitis, pneumonia). 29 patients were treated by recombinant interferon-α2b in the form of rectal suppositories (Viferon) as an addition medication to a common therapy. The results of clinical and immunological analysis showed that use of interferon in case of bronchitis or acute tonsillitis may be unreasonable, but it had relative indications in case of pneumonia
RUDN Journal of Medicine. 2011;(1):162-164
pages 162-164 views

Our authors

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RUDN Journal of Medicine. 2011;(1):165-172
pages 165-172 views

Pravila oformleniya i podgotovki stateyv Vestnik RUDN, seriya «Meditsina»

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RUDN Journal of Medicine. 2011;(1):173-175
pages 173-175 views

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