No 2 (2010)


Changes of blastogenic response of lymphoid cells in kindled animals under the influence of pentoxiphyllin

Kobolev Е.V., Desyatsky V.V., Godlevsky L.S., Mustyatsu V.F., Drozdova G.А.


Under condition of acute experiments on male Wistar rats it was shown that under condition of kindling formation induced via repeated subthreshold corazol administration (30,0 mg/kg, i.p.) the decreasing of blastogenic response induced by bacterial lypopolysaccharide and phytogemagglutinin was shown. This effect was detectable after 10-th convulsant injection and intensified in the course of kindling (21 injections of picrotoxin). Pentoxiphyllin (25,0 and 50,0 mg/kg, i.p.) caused antiseizure effects and effectively prevented kindling-induced decreasing of blastogenic response in dose-depended manner.
RUDN Journal of Medicine. 2010;(2):5-9
pages 5-9 views

Participation of various populations lymphocytes in formation of protection from meningococcosis

Kotelnikova O.V., Drozzina E.J., Volpina O.M., Koroev D.O., Filatova M.P., Alliluev A.P.


Immunization of mice by synthetic peptides fragments of meningococcus external membrane fibers caused the expressed protection of animals against infection caused by live virulent meningococcus culture serogroup A, B and C. There are leading part T-lymphocytes in protection of mice from this infection here. The analysis of T-cellular populations by means of a method flowing cytophluorometrics has shown increase CD4+ and CD8+ lymphocytes without change of parity CD4+/CD8+. The increase in number of these lymphocytes occurred in late terms after immunization of mice.
RUDN Journal of Medicine. 2010;(2):10-16
pages 10-16 views

New views of mildronate use for the prevention and correction of impairment of adaptive processes

Logunova L.V.


Protective and normalizing mildronate action on the level of non enzyme kation proteins in the neurophils and contents of kateholamins in erythrocytes were revealed on the experimental model of the emotional-pain stress. The findings of numerous investigations demonstrate that positive effects of mildronate were connected not only with its metabolism-modifying action but with accumulated holinolike metabolites of karnitine and normalizing influence on the central parts of neuro-endocrine systems, which ensure its use with the aim of increasing of adaptation to the outer environmental factors as well at to the prolonged phycho-emotional overstrain.
RUDN Journal of Medicine. 2010;(2):17-24
pages 17-24 views

Dynamic models and reconstruction of an electrocardiogram at geophysical fluctuations

Pipin V.V., Ragulskaya M.V., Chibisov S.M.


Clause is devoted to consideration of theoretical models of adaptable modes of generation and stability of heart, as nonlinear dynamic dot source. Consideration is limited by research of time dynamics of an electrocardiogram. The comparative description of corresponding mathematical dynamic models available on today is lead. Necessity of creation of as much as possible general model which are based physical laws of processes of the response of heart on external influence is revealed.
RUDN Journal of Medicine. 2010;(2):25-30
pages 25-30 views

Specific features of electrophysical properties of multicomponent heterogeneous systems

Scherbachenko L.A., Borisov V.S., Eine Y.T., Laletin V.G., Belonogov A.V., Baryshnikov E.S., Krasnov P.A., Davydova N.N., Gribacheva O.N.


Electrophysical properties of multicomponent heterogeneous systems containing polar liquid phase and electrically active inclusions are investigated while the study of human blood. It was found that the examined biological system has electret properties which are related to accumulation of interphase charges in the presence of inner electric field. Special attention is paid to the analysis of change of structure of water component in plasma near the interfaces. The existence of low-temperature current maximums whose dynamics is the same for all groups of blood and high-temperature current maximums which characterize individual properties of the biofluid in the range of temperatures (20-220) °C has been established. For the first time electrophysical parameters that describe physical properties of human blood thoroughly are determined.
RUDN Journal of Medicine. 2010;(2):31-38
pages 31-38 views

Intra and interhermispheric coherence peculiarities in foreign language perception

Khokhlova L.A., Deryagina L.E.


Findings of the EEG investigation of students studying English, German, French and Latin are presented in the paper. Cortical activity peculiarities in frequency ranges between 4 and 30 Hz are revealed, EEG determinants of language abilities being estimated. Theta and beta bands are established to be more involved in the process of language perception. English and German cause greater left-hemisphere activity that is particularly marked in parietal, temporal and central regions. Perception of Latin and French is accompanied by the brain activity displacement to the right hemisphere. Results obtained during the investigation point to the close correlations between EEG peculiarities, short-term memory and successful language mastering.
RUDN Journal of Medicine. 2010;(2):39-44
pages 39-44 views

Role of the individual lateral profile in language mastering

Deryagina L.E., Khokhlova L.A.


Findings of the sensory-motor asymmetry investigation are presented in the paper. Four groups of students differentiated on the basis of the dominant hemispheric activation and dominance of the acoustic, visual and motor analyzers are studied, psychophysiological and electrophysiological peculiarities in the examined groups being determined. The individual lateral profile is established to influence the successful language mastering. Results obtained during the investigation point to the close correlations between functional hemispheric asymmetry, types of the higher nervous activity and students' academic achievement.
RUDN Journal of Medicine. 2010;(2):45-50
pages 45-50 views

Acceleration of the adaptation processes in foreign students with cronic associated viral infection: perspective and possibility (as a result of study in programme «Health»)

Kuznetzov V.I., Vyalov S.S., Khodorovich A.M.


The study was research high frequency of chronic associated pathology in the adopted students. These diseases caused delay of adaptation processes, decrease of immunity and increase of morbidity. It was offered the methods of adaptation processes acceleration and morbidity reduction methods in students with chronic pathologic conditions.
RUDN Journal of Medicine. 2010;(2):51-57
pages 51-57 views

Use of plasmapheresis in women with placenta isufficiency after IVF

Buranova F.B., Rogachevskiy O.V.


The effect of plasmapheresis is studied at placentary insufficiency at 120 women after IVF with placenta isufficiency. The age of investigated women was from 26 to 41 years, average 33,4 ± 4,6 years. Among which 60 pregnant treated traditionally, 60 pregnant were treated by plasmapheresis and traditionally. Plasmapheresis (PA) performed discontinuous way. In general, conducted 3 courses of treatment, at intervals of 3-4 days, under the dynamic performance of clinical and laboratory data. The results of our investigation showed that plasmapheresis and in combination with traditionally permits to improve the indications of fetoplacental system and promotes favorable perinatal outcome and pregnancy, labors complication reduced. Researches have shown that plasmapheresis, considerably improves a fetus condition to what the, of USI, Doppler ultrasound and perinatal effects testifies. Improvement of maternal - and perinatal outcomes is noted. Plasmapheresis is a prospective method of treatment allowing to, decrease medicinal loading on maternal and fetal organisms, to improve uterine- and feto-placental circulation, to lower an incidence of complications of pregnancy and delivery.
RUDN Journal of Medicine. 2010;(2):58-64
pages 58-64 views

Hormonal status of young women with connective tissue dysplasia and without it

Ilyina I.Y., Dobrohotova Y.E., Yumina S.V.


Study of hormonal status (hyperandrogenia) on collagen metabolism in young women with connective tissue dysplasia and without it. We can find the collagen destruction of young women with and without dysplasia with hyperandrogenia acodence in comparison with women with dysplasia and without dyshormones prophyl.
RUDN Journal of Medicine. 2010;(2):65-69
pages 65-69 views

Clinico-pathogenetic features of an osteoporosis at the women of genesial age burdened by a cancer of a body and a neck of a uterus, in a state of a medicamental and surgical menopause

Pokul L.V., Evtushenko I.D.


In this article clinical indexes of the dynamics of mineral bone density according to both densitometry and marker of resorption as well as bone formation and steroid blood hormons in patients in postovarioectomy are analysed. These patients state was complicated by cancer of the corpus and colli uterus after etiopathogenetic treatment including total husterectomy, radiation therapy and polychemotherapy. According the results of the comparative analysis in patients with postvarioectomic syndrome developed after surgical treatment for benign internal genitalia diseases we may make the conclusion on pathogenetic role of postovarioectomic syndrome in the development of bone disturbances in female patients which underwent total hysterectomy and special therapy.
RUDN Journal of Medicine. 2010;(2):70-76
pages 70-76 views

Psychophysiological characteristics of perception in auditory deprived children

Aleksanyan O.V., Endolov V.V., Carpacheva G.V., Torshin V.I.


Characteristics of brain functional interhemispheric asymmetry was investigated in 6-11 old auditory deprived children. Method by Homskaya (1995) of functional interhemispheric asymmetry determination was used. Predominant hand (6 tests), leg (6 tests) and eye (6 tests) were determined in each child for motor and sensory asymmetry estimation. Tendency in functional interhemispheric activity rearrangement with increasing activity of right hemisphere for motor control and visual perception was revealed in deaf children and adolescent.
RUDN Journal of Medicine. 2010;(2):77-82
pages 77-82 views

Tissue Doppler study in the diagnosis of functional disorders of the myocardium in patients with chronic heart failure

Skosyrev A.S., Maksimkin D.A.


The article presents a comparative analysis of standard echocardiography and tissue Doppler method Rings atrioventricular valves in patients with chronic heart failure with a view to early diagnosis of functional disorders of the myocardium. It is shown that, in connection with the ability to detect myocardial dysfunction in the earlier periods of chronic heart failure and the possibility of dynamic observation of patients during therapy, appropriate complement adopt routine echocardiography by tissue Doppler.
RUDN Journal of Medicine. 2010;(2):83-88
pages 83-88 views

Level of hormones of the adrenal and thyroid glands in the early period of a burn shock

Chekushkin A.A., Mozerov S.A., Mitroshin A.N., Myalin A.N., Kruglyakov P.P.


The results of investigation the level of hormones of the adrenal and thyroid glands are reflected in the article: there are hydrocortisone, aldosterone, thyroxine, triiodthyronine during 24 hours of burn shock. The study testify an increase in the level of of glucocorticoids in the blood at the same time decrease in the level of the thyroid hormons.
RUDN Journal of Medicine. 2010;(2):89-92
pages 89-92 views

Clinical effectiveness of dynamical electroneurostimulation in combined therapy for hypertension

Svinsova G.A., Kobalava G.D., Bagmanova N.K., Kotovskaia U.V.


To study possibilities of improving of blood pressure (BP) control using the DENS device in patients with arterial hypertension stages I-II. Placebo-controlled study of antihypertensive effect of diaDENS-cardio in 60 patients with arterial hypertension taking regular antihypertensive therapy. Measurements of BP were performed by self BP control and 24 hours monitoring of BP. According to results of both self BP control (123,4 ± 5,4 vs 144,9 ± 7,4 мм рт.ст., p < 0,05) and 24 hours monitoring of BP (125,8 ± 4,9 vs 147,1 ± 11,7 mm Hg, p < 0,05) decrease in systolic BP in groups using device diaDENS-cardio was observed. Decrease in BP in patients using device diaDENS-cardio resulted in reduced doses of ACE (enalapril 7,8 ± 5,7 vs 19,7 ± 10,2 mg/days, p < 0,01) and beta-blockers doses (metoprolol 40,8 ± 19,1 vs 75,8 ± 35,6 mg/days, p < 0,05) for optimum BP control. Using of active device diaDENS-cardio in patients with arterial hypertension helps to attain targeted BP values with lower drug doses.
RUDN Journal of Medicine. 2010;(2):93-98
pages 93-98 views

Treatment of damage of the rotary cuff of the humeral joint with use of art roskopichesky technics

Majdi Zahra -., Savitskiy P.P., Kopylov А.А., Lazko F.L.


The trauma was the basic provoking factor in development of the given pathology. Patients were treated is out-patient at the traumatologist, the surgeon or the neurologist on a residence with the diagnosis a bruise of a humeral joint, a cervical osteochondrosis, arthrology. For the purpose of elimination and preventive maintenance of an impingement-syndrome and subacromion bursitis operation with application artroskopichesky technicians is spent. At damage of a rotary cuff arthroscopies a humeral joint spent for diagnostics with the subsequent open surgical intervention for the purpose of restoration of integrity of a rotary cuff.
RUDN Journal of Medicine. 2010;(2):99-104
pages 99-104 views

About the ways of restoratory medicine aid organization improvement

Prilipko N.S., Bobrovnitskiy I.P.


The Article presents the stages of rendering restoratory medicine medical aid. It proposes the procedure of in-patient as well out-patient and polyclinic treatment of individuals with risk factors and patients and the requirements for sending patients for restoratory treatment and medical rehabilitation. The Article proves that the enlargement of rehabilitation and restoratory treatment complex individual programs medical institutions network would make it possible to decrease the term of incapacity for work with acute diseases, disability, especially, among able-bodied population.
RUDN Journal of Medicine. 2010;(2):105-110
pages 105-110 views

New methods of laboratory training performance

Igumnova O.V., Shimkevich E.M., Ananuin D.A., Gordon C.B., Lukyanova E.A., Protsenko V.D.


Medico-biological laboratories in Russian institutes of higher medical education do not support effectively the educational process. Development of universal criteria and requirements to modeling of a virtual medico-biological laboratory is significant for medical education. The purpose of the article is to develop principal approaches to realization of the model in a virtual medico-biological laboratory.
RUDN Journal of Medicine. 2010;(2):111-116
pages 111-116 views

Case of radical correction of pulmonary atresia with anomali of origin of left pulmonary artery from ascending aota by conduit implantation

Deigheidy E.M.


The use of conduit in the radical correction of complex congenital heart disease (CCHD), such as pulmonary atresia, ventricle septal defect (II type) with origin of left pulmonary artery from ascending aorta, is the operation of choice in the presence of anomalous origin of coronary arteries at anterior wall of right ventricular outflow tract (RVOFT).
RUDN Journal of Medicine. 2010;(2):117-119
pages 117-119 views

To the assessment of results of treatment of abdominal polytrauma

Pugachev A.N.


622 patients with abdominal polytrauma were studied. At the time of admission frequency of shock was 70%. Found that with the progression of shock is activation of the sympathetic-adrenal system, which is most significant in traumatic shock. The overall mortality rate was 10,77%. The level of mortality depends on the severity of shock, the time pre-hospital period and the dominant injury.
RUDN Journal of Medicine. 2010;(2):120-122
pages 120-122 views

Abilities of the tension-free repair at the treatment of the incarcerated incisional wall hernias

Abakshin N.S.


524 patients with incarcerated wall hernias were studied. Postoperative complication rate was 19,9%, mortality rate was 8,6%. Recurrence rate was 18,6%. It depends on intraabdominal pressure and function of the external respiration. Tension-free repair appears to be safe, and is proving to be effective as it decreases intraabdominal pressure, complications, recurrences, and mortality rate.
RUDN Journal of Medicine. 2010;(2):123-124
pages 123-124 views

Results of application ultrasonic therapy in treatment of relapses of ulcers and purulent complications of the diabetic foots

Kislyakov V.A.


Have applied ultrasonic therapy device URSK-7N-22 during surgical treatment at 25 patients with relapses of ulcers and it is purulent complications of a diabetic foots. Neuroichemic the form - at 15, neuropathy - at 10. Control group - 20 patients: women - 11, men - 9. Term of treatment was reduced to 5-6 days.
RUDN Journal of Medicine. 2010;(2):125-127
pages 125-127 views

Our authors

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RUDN Journal of Medicine. 2010;(2):128-129
pages 128-129 views

Pravila oformleniya i podgotovki stateyv Vestnik RUDN, seriya «Meditsina»

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RUDN Journal of Medicine. 2010;(2):130-132
pages 130-132 views

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