No 3 (2009)


Plasmid gene expression of Escherichia coli drug resistance under the influence of electro-magnetic radiation

Pronina E.A., Shub G.M., Shvidenko I.G.


This article gives the account of the research results of electro-magnetic influence on a frequency of nitric oxide absorption and radiation molecular spectrum (150 GHz) and atmospheric oxygen absorption and radiation molecular spectrum (129 GHz) on the sensitivity of Escherichia coli to several antibiotics. The panoramic spectrometric measuring complex, developed in Central Scientific Research Institute of measuring equipment Public corporation, Saratov, was used while carrying out the research. Electromagnetic vibrations of extremely high frequencies were stimulated in this complex imitating the structure of atmospheric oxygen and nitric oxide absorption and radiation molecular spectrum. The experiments that were carried out indicate the influence of radiation on chosen frequencies on the gene expression of drug resistance.
RUDN Journal of Medicine. 2009;(3):5-9
pages 5-9 views

Investigation of the interaction of Bifidobacterium bifidum 1 and Escherichia coli M-17 in the bificol praparation during their simultaneous cultivation

Ladygina A.V.


Using the model of biocompatibility the complicated mechanism of interaction between the B. bifidum 1 and E. coli М-17 was revealed during the simultaneous cultivation of these strains. Bifidobacteria and the products of their metabolism were shown to inhibit the growth of E. coli, at the same time the products of metabolism of E. coli stimulate the growth of Bifidobacteria.
RUDN Journal of Medicine. 2009;(3):10-14
pages 10-14 views

Features of accumulation of microcells in bodies of urinogenital system

Zaitsev I.V., Zaitsev V.F.


Infringements in maintenance in an organism of the person can be traced during all life. Presence in an environment of the raised maintenance of the some people and microcells, toxic for an organism of the person, in opinion of many authors, promotes occurrence of a background on which various diseases can develop. The salts of heavy metals contained in the Volga water (one of the basic sources of receipt of microcells in an organism of the person), are dominating among other toxicant for the population of the Astrakhan region. The submitted data can be used as the additional laboratory criterion reflecting risk of development of avarious pathology of urinogenital system.
RUDN Journal of Medicine. 2009;(3):15-19
pages 15-19 views

Influence opioids on oxidizing stress and sphingosine way of activation of apoptosis in kidneys

Belous Y.A., Komarevtseva I.A., Komarevtseva K.V.


It was established that dalarginum injection before AKF (acute kidney failure) formation prevented decrease of the contents sphingosine and fragmentations DNA, increas of SOD (superoxiddismutase) in the kidneys. The probability of correlation connection between at the activation of sphingomyelin cycle and the state of antioxidant systems which can influence on the regulation of apoptosis is determined.
RUDN Journal of Medicine. 2009;(3):20-27
pages 20-27 views

Specificity of the metabolism response, caused by AB0-belonging on action of biologically active materials

Gusyakova O.A., Zubova I.A., Sidorova I.F., Ryskina E.A., Dzugkoev S.G., Myakisheva Y.V., Pavlova I.O., Baisheva G.M.


Erythrocytes' quantitative and structurally functional parameters of clinically healthy persons with various АВ0-belonging were studied. Group-specific features of the given cells were revealed. Dependence of the metabolic answer character to action of biologically active materials of an exogenous and endogenous parentage on a AB0-group is studied. It is established, that the most expressed changes of erythrocytes indicators under the influence of a pyruvate, oxaloacetate, ethanol and silistrong are observed at persons with the fourth blood groups. The received results open molecular bases of the specific answer of an organism on action of endogenous and exogenous bioregulators.
RUDN Journal of Medicine. 2009;(3):28-33
pages 28-33 views

Comparison of medicamental secondary prevention of cardiovascular disease in ambulatory patients with myocardial infarction over a period of 2001-2006 (pharmacoepidemiological study)

Fitilev S.B., Vozzhaev A.V., Shkrebneva I.I., Titarova Y.Y., Sicheva E.A., Zhuravlev R.I.


The two-stage retrospective review of 1375 medical records of ambulatory patients with myocardial infarction was carried out in order to assess the delivery rate of up-to-date international and domestic guidelines for secondary CVD prevention over a period of 2001- 2006. The gap between the current guidelines for medicamental prophylaxis and their implementation in clinical outpatient practice was revealed. In spite of the fact that doctors began to prescribe preventive drugs more often target levels for cholesterol and blood pressure were not achieved in the major part of patients with myocardial infarction. The prescription rate of antiaggregants, anticoagulants and statins is still rather low.
RUDN Journal of Medicine. 2009;(3):34-36
pages 34-36 views

Pharmacoeconomical aspects of the treatment of arterial hypertension in patients with type II diabetes mellitus in outpatient department

Gushina J.S., Loskutova E.E., Lepakhin V.K.


Diabetes mellitus II (DMII) is a chronic disease that has a major social impact. A substantial proportion of the costs of diabetes treatment arises from treating long-term complications, particularly cardiovascular disease (CVD). Arterial hypertension increases risk of CVD in patients with DMII. The objective of this study was to estimate costs of managing arterial hypertension in patients with DMII in different outpatient departments. It was detected higher level of costs of medical care in general practice department, but provide maximal benefit to the treatment of arterial hypertension in such group in specialized agency.
RUDN Journal of Medicine. 2009;(3):37-40
pages 37-40 views

Possibilities of quantitative sensory testingto assess dysfunction of small fibers in patients with compression lumbo-sacralradiculitis

Shaova L.S., Kotovskaya Y.V., Kabalava Z.D., Sokov E.L., Kornilova L.E.


Surveyed 55 patients with clinical displays of neuropathic pain syndrome in consequence of compression radiculitis L5, S1 which has been proved by MRT/CT and pain questionnaires. Quantitative sensory testing (QST) was performed to assess loss of sensory function for two dermatome body areas (one affected and normal area): thermal detection thresholds for the perception of cold and warm, thermal pain thresholds for cold and warm stimuli. The results showed dysfunction of small fibers on affected low limb and unaffected low limb. There also were founded combination of cold hyperalgesia and allodinia and closely correlation of QST-parameters with questionnaires results.
RUDN Journal of Medicine. 2009;(3):41-46
pages 41-46 views

Thrombolytic therapy and cardiac free wall rupture in patients with acute myocardial infarction

Zeltyn-Abramov E.M., Radzevitch A.E.


The possible connection between thrombolytic therapy (TT) and the risk of left ventricle free wall rupture (LVFWR) in patients with acute myocardial infarction with ST-elevation (STEMI) is the point of discussion. The purpose of the study is evaluation of lethal outcomes among patients with STEMI. The retrospective analysis of medical data, including autopsy reports was performed. All data were divided in two groups: 210 case reports without TT and 188 reports with TT performed. Obtained data demonstrate the evident prevalence of LVFWR among patients, treated with TT: 52,4% vs 20,0% independently of myocardial reperfusion achieved. The evaluation of LVFWR risk at concrete patient with STEMI is strongly recommended.
RUDN Journal of Medicine. 2009;(3):47-51
pages 47-51 views

The combined used of homeopathy and dynamic electroneurostimulation in improvement qualities of the sexual life of men

Agasarov L.G., Gurtskoi R.A.


The deterioration of a sexual life revealed approximately at third of conditionally healthy men, defines necessity of carrying out of regenerative actions. A subject of the present research was the analysis of application with the similar purpose of a complex of homoeopathy and dynamic electroneurostimulation (DENS). By results of work it is confirmed, that the offered technology surpasses in productivity (dynamics of subjective and objective characteristics) compared variants of influence - separately homoeopathic or DENS against platsebo-therapy.
RUDN Journal of Medicine. 2009;(3):52-56
pages 52-56 views

Correction of neuropsychological disturbances at patients of polycythemia vera by hirudotherapy

Zubarkina M.M., Zhernov V.A.


In article results of scientific researches of employees of a unit of restorative medicine are presented possibilities hirudotherapy in correcting of neuropsychological frustration at patients polycythemia vera without use of medicaments.
RUDN Journal of Medicine. 2009;(3):57-59
pages 57-59 views

Short-term results of radical correction of the general arterial trunk with high pulmonary hypertension

Gorbachevsky S.V., Maltsev S.G., Deigheidy E.M., Gorchakova A.I.


This study concerning of the retrospective analysis of the effects of pulmonary hypertension on mortality of patients with radical correction of common truncus arterusos. From 1984-2004, 54 patients were operated. Normalization of pulmonary blood pressure could take place in 77% of operated patients with common arterial trunk (common truncus arterusos), which had a high pulmonary hypertension.
RUDN Journal of Medicine. 2009;(3):60-65
pages 60-65 views

Surgical repair of fractures involving the orbital floor

Sandoval J.M., Gunko V.I.


Authors report their experience in the treatment of fractures involving the orbital floor. A total of 14 patients passed pre and post-operative clinical and radiological assessment. Of the 14 patients, the zygomatic-maxillary-orbital complex was involved in 6, isolated fractures of the orbital floor blow-out in 8. In all the cases transantral approach was used. In fractures involving the zygomatic-maxillary-orbital complex, apart from repair of the orbital floor, fixation of «standard» junctions' points was made. In isolated fractures of the orbital floor blow-out, «bone-plastic antrotomy» method was used. This one may be defined as variant of classical antrotomy what don't leave bone defect on the frontal wall of the maxillary sinus. In all the cases titanium material was used for osteosynthesis: mini-plates or mesh. The last one was employed in four patients due to substantial bone loss. Functional and aesthetic deficits were resolved in all patients. Long-term results showed complete recovering of binocular eyesight and absence of enophthalmos.
RUDN Journal of Medicine. 2009;(3):66-70
pages 66-70 views

State of the fermentable antioxidant system of blood, prostate secret and ejaculate at standard treatment of chronic abacterial prostatitis/syndrome of chronic pelvic pain (CAP/CPPS IIIA)

Shangichev А.V.


Activity of superoxiddismutase (SOD) and catalase (CT) in blood, secret of prostate and ejaculate of 42 patients with CAP/CPPS IIIA before and in 1 month after standard treatment, had been investigated. Activity of SOD in blood has been lowered in comparison with norm on 15,6% (p < 0,05), and in a prostate secretion and in ejaculate is increased on 42,1% (p < 0,05) and 38,1% (p < 0,05). КТ Activity was 24,5% (p < 0,05), 31,6% (p < 0,05) and 28,8% (р < 0,05) higher in blood, prostate secret and ejaculate before treatment. After treatment activity of SOD is in blood, prostate secretion did not differ from the control. SOD Activity in ejaculate remained increased on 30,6% (p < 0,05). The indexes of catalase activity went down and did not differ from the control. Changes of SOD and CT activity in blood, prostate secretion and ejaculate of patients with CAP/CPPS IIIA testify to the expressed fermentation misbalance of antioxidant defense and about development of free radical pathology. Determination of SOD and CT activity in blood, secretion of prostate and ejaculate can serve as the biochemical criterion of development of inflammation and can be used for monitoring of efficiency of treatment of patients with CPPS IIIA.
RUDN Journal of Medicine. 2009;(3):71-75
pages 71-75 views

Use of ozone in women with placenta insufficiency after IVF

Buranova F.B., Federova T.A.


The effect of ozone therapy is studied at placentary insufficiency at 120 women after IVF with placenta isufficiency. Among which 60 pregnant treated traditionally, 60 pregnant were treated by ozone therapy and traditionally. The results of our investigation showed that ozontherapy and in combination with traditionally, permits to improve the indications of fetoplacental system and promotes favorable perinatal outcome and pregnancy, labors complication reduced. Researches have shown that ozone therapy considerably improves a fetus condition to what the, of USI, Doppler ultrasound and perinatal effects testifies. Improvement of maternal and perinatal outcomes is noted. Ozonotherapy is a prospective method of treatment allowing to, decrease medicinal loading on maternal and fetal organisms, to improve uterine and feto-placental circulation, to lower an incidence of complications of pregnancy and delivery.
RUDN Journal of Medicine. 2009;(3):76-80
pages 76-80 views

Immunohistochemical assessment angioarchitecture a vaginal side at women in a postovariectomy state

Pokul L.V., Evtushenko I.D., Chuhrai O.U.


In article the disturbance problem of blood flow the vaginas of the woman in a state of a medicamental and surgical menopause after spent этиопатогенетического the treatment including total husterectomy, radiation therapy and polychemotherapy by results of an expression Cd34 and bloods steroid sexual hormonesis, in particular aestradiolum. Comparison with bunch of women in a state of the postovariectomy which have educed after surgical treatment concerning good-quality diseases of internial genital. The pathogenetic role of surgical and radial influences on a vagina of the woman is proved.
RUDN Journal of Medicine. 2009;(3):81-86
pages 81-86 views

Features of the formation of neurovegetatioe reaction in ontogenesis of frequently ill children

Useynova N.N., Kolmakova T.S., Shovkun V.A., Mizernitsky Y.L.


There have been examined 360 children aged till three years of life hospitalised with the diagnosis of acute respiratory disease. All children have been divided into two groups: sporadic ill ones (frequency of catarrhal diseases 1-2 years) and frequently being ill children (frequency of catarrhal diseases 4-6 year). The influence of psychosocial and medical-biological factors on frequency of disease has been carried out, and it has also been defined the content of biogenic amines in blood - adrenalin (A), noradrenalin (NA), dopamine (DA) and serotonin. The analysis of the findings was carried out on the age rotation. The research results of a sporadic being ill children have shown the adrenergic regulations of visceral functions to prevail in the first months of life and it is gradually getting weaker conceding to noradrenergic system which reflects heterochronia of maturing nervous regulation life-support systems in the first years of life. At a frequently being ill children a corresponding dynamics of indicators of adrenaline and noradrenalin content in blood was lacking and that gives us the basis to speak about an arrest of development of sympathetic regulation of vegetative maintenance at the children of that group. The results of research allow us to say also about infringement of formation of functional mutual relations between noradrenergic and dopaminergitic links of vegetative regulation in the first years of life and that can be one of the reasons of low stress of stability of a high frequency of morbidity.
RUDN Journal of Medicine. 2009;(3):87-92
pages 87-92 views
pages 93-95 views
pages 96-98 views

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