RUDN Journal of MedicineRUDN Journal of Medicine2313-02452313-0261Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)13591Thrombolytic therapy and cardiac free wall rupture in patients with acute myocardial infarctionZeltyn-AbramovE MКафедра терапии № 1Факультет последипломного образования; Московский государственный медико-стоматологический университет; Moscow State University of Medicine and Dentistry-RadzevitchA EКафедра терапии № 1Факультет последипломного образования; Московский государственный медико-стоматологический университет; Moscow State University of Medicine and Dentistry-Moscow State University of Medicine and Dentistry150320093475118092016Copyright © 2009,2009The possible connection between thrombolytic therapy (TT) and the risk of left ventricle free wall rupture (LVFWR) in patients with acute myocardial infarction with ST-elevation (STEMI) is the point of discussion. The purpose of the study is evaluation of lethal outcomes among patients with STEMI. The retrospective analysis of medical data, including autopsy reports was performed. All data were divided in two groups: 210 case reports without TT and 188 reports with TT performed. Obtained data demonstrate the evident prevalence of LVFWR among patients, treated with TT: 52,4% vs 20,0% independently of myocardial reperfusion achieved. The evaluation of LVFWR risk at concrete patient with STEMI is strongly recommended.thrombolitic therapyacute myocardial infarctionтромболитическая терапияострый инфаркт миокарда