Vol 21, No 1 (2017)

The article presents the tactics of treatment of elderly patients with fractures of the femoral neck. Depending on the nature of the fracture, the period from the date of injury presented by the selection of a method of surgical treatment of fractures of the proximal femur.with biomechanically favorable fractures of the femoral neck Pauwels type I-II with displacement of fragments of type Garden II-III up to 3 days after the injury we have produced a minimally invasive percutaneous osteosynthesis beam V-shaped spokes or AO cannulated screws.If after an injury took place over 3 days in patients older than 60 years at subcapital fractures type III of Pauwels, Garden IV of, patients produce primary hip arthroplasty. The article also describes the experience of doing pereoperatsionnogo elderly patients with femoral neck fractures in the preoperative and postoperative phases.

The concentration of total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C) were determined among students of PFUR aged 17-25, from different climatic and geographical regions. In all the concentrations (> 6.2 mmol/L) of total plasma cholesterol were detected at 6 (2.4%) students, indicating a high or very high risk of coronary heart disease (CHD). Elevated levels of plasma LDL-C (> 3.31 mmol/l) were found at 4 (1.6%) students, indicating a high or very high risk of coronary heart disease. Lower concentrations of HDL-C plasma (< 1.31 > 1.1 mmol/L) were detected at 30 (12.4%) indicating a moderate risk of CHD and at 11 (4.6%) students concentration of HDL-C were lower (1,1 mmol/L), indicating a high risk of coronary heart disease. The results can be used as a justification for the screening survey to identify dyslipidemia among adolescents and young adults, with the subsequent conducting of the individual preventive and therapeutic measures.

Haloperidol is used in the practice of drug for relief of updating drives in patients suffering from a pathological attraction to alcohol, but the empirical selection of its dosage often leads to the development of patient adverse drug reactions. Synthesis of glycoprotein P, involved in the excretion of various xenobiotics including haloperidol encoded ABCB1 gene having a high level of polymorphism. Various ABCB1 allelic variations are associated with varying degrees of activity of glycoprotein P. Polymorphism 3435C>T is the functional polymorphism, which makes the activity of glycoprotein P slowly, that’s why its increase the level of concentration of xenobiotics (substrates of glycoprotein P) in blood-plasma and increase the risk of adverse drug reactions. Efficacy and safety of treatment with haloperidol was determined by international psychometric scales and scales for measure of extra pyramidal adverse drug reactions. ABCB1 genotyping was performed by polymerase chain reaction in real time (Real-time PCR) using allele-specific hybridization. According to the survey were identified statistically significant patterns between ABCB1 polymorphism and the efficacy and safety profile of haloperidol.

The article states the concept of chronic lateral instability. There are presented epidemiology, anatomy, ankle, lateral ligaments of the ankle, including the functional significance and anatomical features of each bundle, in details described diagnostics, research methods, including ultrasound, MRI, X-rays, clinical research methods of chronic anterior lateral instability: “front drawer” test, “supination test”, “titltest”, “pronation test”. The artile shows classification of AOFAS scale. Historical background of operational techniques and their various modifications in chronic anterior lateral instability of the ankle are highlighted, showing the results before and after presentated operating procedures. Tactic of conservative treatment is marked. There are presented results of open and closed types of anatomical and nonatomical stabilization damaged front-fibular ligament the talus. The results of operations of the tendon tenodesis short and long tibial muscles and Brostroma operations and their modifications, as well as modern operating arthroscopic surgery of this pathology, are described. Marked are the advantages and disadvantages of the anatomical and nonanatomicalstabilization of damaged front-fibular ligament of the talus. During instability of the ankle joint young patients with high physical activity, involved in sports, with concomitant rupture of the anterior talo-fibular and calcaneal-fibular ligaments - the treatment method is tenodesis of outer ligament complex form the semitendinosus tendon with tunneling in the fibula, calcaneus and talus. For patients with low physical activity, not involved in sports, whose professional activity is not associated with heavy physical work, it is possible to perform the Brostroma-Gould operation - to create duplikatury local fabrics. Non anatomical ankle stabilization operations, including tenodesis tendons, often lead to disruption of gait and foot inversion restriction and are not recommended for widespread use.

The most promising way to reduce maternal and perinatal morbidity and mortality and also obstetric aggression is a preliminary forecasting of adverse perinatal outcomes, i.e., an assessment of a perspective perinatal risk. Object: to estimate the role of perinatal risk factors in the forecasting of delayed abdominal delivery. We found that increase of perinatal risk factor in delayed abdominal delivery occurs during the whole pregnancy, but 3d trimester's complications make the greatest contribution.

According to the results of a poll conducted among 157 final year students of the Stavropol basic medical college is composed of the social portrait - this is 23-25 years old young woman, who plans to work in her specialty, mainly in the hospital. The choice of the profession due to such factors as the possibility of providing assistance and constant communication with people. She is going to look for work mostly through acquaintances. She believes that after graduating from the medical college she will be practically ready to perform professional duties, but she hopes to the mentor’s help in the workplace.

Social monitoring of disability occupies a special place among health, social and economic problems of vital national importance. The relevance of the study lies in the fact that it continues to grow, the primary disability of the working population, which significantly affects the economy of our country. Monitoring disability to allow us to trace the main trends in the indicators and to conduct appropriate activities in public policy. The aim of this work is to monitor the structure of primary disability among persons of working age in the Ryazan region. Objectives of the study: monitoring of process primary disability for a certain period of time; identifying emerging trends and dynamics of primary disability in individuals of working age; forecasting emerging trends and their development; finding ways to prevent negative trends and maintaining positive trends in the development process. In the analytical review of official data from Rosstat, shows the dynamics and trends of disability in the Ryazan region. In the course of the study studied the regularities of formation of disability to reflect the classes of disease, determined the prevalence of disability among the adult population.

One of the important tasks of the state - is to reduce morbidity, mortality and disability due to malignant neoplasms. It can be solved through the protection of public health, including timely medical examination and rehabilitation, as well as promoting a healthy lifestyle. However, unfavorable ecological situation, the effects of widespread use of a variety of special equipment, deterioration of social well-being of the population and the abuse of tobacco and alcohol adversely affect the steady increase in the incidence of malignant tumors, and experts predict it is expected to further increase. Negative epidemiological situation on the malignancy has developed both in Russia and around the world. Oncopathology causing considerable economic damage to the country. All of the above leads to the relevance of a complex problem and requires further examination. In order to determine priorities in the organization of cancer care was necessary to study the state of oncology service data in the Republic of Bashkortostan in comparison with the all-Russian figures in dynamics for the last five years (2011-2015 gg.). The study found that the quantitative and qualitative indicators of cancer care in the Republic of Bashkortostan (active detection, timely diagnosis, morphological verification of the diagnosis, the five-year survival rate, index of accumulation of contingents, the incidence of malignant tumors) do not exceed the all-Russian figures. The dynamics for five years there has been a positive dynamics of the studied parameters, but about a quarter of patients who for the first time identified a cancer die within the first year after diagnosis. A study of performance indicators oncology service is of considerable practical interest because it can serve as a basis for planning the organization of oncological aid to the population, the development of national and regional anti-cancer program, to determine the required volume of curative and palliative care, the organization of medical and social rehabilitation of the sick and disabled. Improving cancer institutions in the country and the region will allow to provide specialized assistance to the population, corresponding to modern scientific and technical development of medical science, regardless of the place of residence of a particular patient.

There are many measures for the effective functioning of the system of health protection of women and children in the Samara region: organizational, improving the system of legal norms, aimed at the optimization of medical aid to mother and child, strengthening the material-technical base of medical institutions, mastering modern methods of diagnosis and treatment, training of medical personnel at a high level. Plan of measures of structural transformation health care delivery system on women and children included the adoption of the regional target program “Health of the Samara region children” for 2013-2015. Within the framework of its implementing are used new prevention technologies affecting on indicators morbidity and mortality of the child population.