No 1 (2015)

The article presents a historical analysis of the medical information-analytical center as a key element of health information support system of the RF subjects, provides analysis of the dynamics of activity of the institutions, including financial and personnel resources. Settle the improvement of the normative-legal basis, organizational structure, operations centre-based logistics concept and the implementation of new computer technologies.

The article on the materials of Samara city given detailed medical and social characteristics for ensuring availability, duration of expectation of medical reception, possibility of receiving paid medical services at an affordable price and satisfaction of mothers in the pediatric clinic with provided information on interesting questions.

The article analyzes data on crimes of violence against women and children victims in the territory of the Russian Federation, Central Federal District, in the regions of Ryazan’ and Tver’. Among the causes of death of women special consideration was given to the medical and social problem of violent deaths, including murders and suicides.

Nowadays a great number of different questionnaires and forms for to assessment of quality of life (QL) of patients, including patients with morbid obesity, have been developed and used. To estimate the QL, we used three questionnaires: SF-36, GIQLI and the original one assessing the quality of life index (QLI), developed by us specifically for patients with morbid obesity. The main group consisted of 26 patients with morbid obesity, the av. age of which was 36,7 ± 0,3 years, the av. weight - 125,1 ± 24,5 kg (from 93 to 160 kg) and the av. BMI - 42,8 ± 8,1 kg/m 2. The control group consisted of 26 healthy persons without any comorbidities and morbid obesity. All indicators in all groups are higher than in healthy persons (the difference is statistically significant (р £ 0,05). From these data it follows that, as in the case of SF-36 questionnaire, there are significant differences between the two groups in all blocks of questions indicating a lower level of QL in patients with morbid obesity compared with healthy. Similar results were obtained in the analysis of QLI. Analysis of the three questionnaires revealed that all demonstrated a significant difference between the QL in patients with morbid obesity from that of healthy persons. These figures differ both in total points and in individual clusters of questions. A study of the correlation between BMI and levels of QL showed that, according to the GIQLI questionnaire has not represented. According to the questionnaire SF-36 there is inverse dependence between indicators of physical well-being and body weight of the patient. The same relationship exists in the QLI questionnaire in the block of disease-specific questions.

The article presents a system of measures aimed at preserving and improving the health of the working age population living in the closed administrative-territorial formation - Ozyorsk city. The priority areas of medical and organizational, preventive and informational nature are highlighted.

This study was performed to evaluate symptoms of uterine fibroid and their impact on the quality of life after treatment using a validated questionnaire. It is shown that the assessment of quality of life not only a predictor of the complicated postoperative period and the remote recurrence of a disease, as well as the criterion of full course of rehabilitation. Preference of UAE leads to sustained improvement in the quality of life and to a significant relief of symptoms with the greatest recovery after comprehensive rehabilitation.

Results of clinical trial and information about new developed medical devices for UV corneal collagen cross-linking at Ufa eye research institute are given.

The 276 children on mechanical ventilation in the neonatal period the study was conducted tracheobronchial aspirate (TBA) with the release of pepsin and the determination of its extinction activity value. It was found that the increase of pepsin activity was accompanied by increased duration of mechanical ventilation and subsequent oxygen therapy.

Physico-chemical and biopharmaceutical analysis excipients and drug indicates the absence of the previously announced their inertia. Excipients can exhibit biological activity by themselves, and influence the activity of the active compound. Previously, we have shown that the water depleted in deuterium reduces the toxic effect of disodium ethylenediaminetetraacetate (Na 2EDTA). Disodium edetate is used as a stabilizer in liquid dosage forms including ointments, suppositories and tablets, is known as E386 preservative in the food industry. Zinc is as essential trace elements involved in many vital processes and is a part of the multi-component drugs. We have studied the combined toxicity of adjuvant Na 2EDTA and zinc salts in solutions with different ratios of isotopes of hydrogen (D/H) on biological models Spirotox.