Prediction of the risk of severe pre-eclampsia in multiple pregnancies and ways of its prevention

S V Barinov; Баринов Сергей Владимирович; E V Rogova; Рогова Елена Владимировна; T V Kadtsyna; Кадцына Татьяна Владимировна; D G Novikov; Новиков Дмирий Гергиевич; I N Rasdobedina; Раздобедина Ирина Николаевна

Prediction of the risk of severe pre-eclampsia in multiple pregnancies and ways of its prevention

Authors: Barinov SV¹, Rogova EV¹, Kadtsyna TV¹, Novikov DG², Rasdobedina IN³
Affiliations:
1. Omsk State Medical Academy
2. Omsk state medical Academy
3. maternity hospital, BOOZOO OKB
Issue: No 1 (2015)
Pages: 69-76
Section: Articles
URL: https://journals.rudn.ru/medicine/article/view/3174

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Abstract

Based on the study of indicators of oxidative and antioxidative activity of blood, acute phase protein - lactoferrin, placental growth factor (P1GF)) in the first trimester of pregnancy 6-10 weeks in serum of 226 pregnant women with preeclampsia and multiple pregnancy is developed and implemented a complex of therapeutic and diagnostic procedures, which helped to reduce the risk of severe preeclampsia in 2 times, massive bleeding in 1.2 times and to improve perinatal outcomes due to prolongation of pregnancy ( r = 0,78, p < 0,01).

Keywords

multiple pregnancy, growth factor, placenta, oxidative stress, preeclampsia, placental insufficiency

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Vol 29, No 1 (2025)

Prediction of the risk of severe pre-eclampsia in multiple pregnancies and ways of its prevention

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Abstract

Keywords

About the authors

S V Barinov

E V Rogova

T V Kadtsyna

D G Novikov

I N Rasdobedina

References

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