No 2 (2012)

In the present research the visualization of amplitude-phase relationships in entrainment processes is based on the expression serial time sections [3] allow tracing the behavior of different parameters of any rhythmical component of spectrum during a time which includes spans before, during and after any synchronizing (desynchronizing) event. There is a simple and noninvasive method for acquiring information on the visualization of amplitude-phase relationships. The method used the mathematical and graphic analysis simultaneously visualization the dynamics of amplitude, its statistical significance and acrophase in entrainment processes, the three modifications of serial sections was elaborated: procedure of adding logarithms of P-values-matrices, plotting 2D image and 3D image. As examples for illustration serial section method, automatic measurements of blood pressure (BP), both systolic (S) and diastolic (D), and heart rate (HR) were used. Five flights from Minneapolis (USA) to Saint-Petersburg (Russia) crossing 9 time zones and 4 flights in the opposite direction were performed during that time (during the second return flight, no measurements were taken). The simultaneous drop in amplitude and the rapid shift in acrophase associated with West-to-East flights, and more gradual changes for East-to-the-West flights led to the hypothesis that the rapid entrainment is performed by collapse of the rhythm at a singularity time point. Application of the present method has allowed the authors to carry out visualised dynamic chronobiological the control parameters of cardiovascular system. The method has higher diagnostic value in comparison with well-known procedures of an estimation of chronomedicine.

Conformity to hygienic air ion formula of working offices, classrooms and chemistry laboratory in which the work with volatile organic solvents are conducted, as well as to a city apartment and a country house is investigated. Concentration of air ions was measured using the counter «Sapphire 3М». Parameters of the air ionization: concentration of ions of both charges (N and N-, ions/cm3) and unipolarity coefficient (K = N/N-) were evaluated. The quantity of air ions did not correspond to sanitary and hygienic standards in all areas except of a country house. Additional artificial air ionization and ventilation in classrooms and chemistry laboratories offered to use.

According to the program of blooding surgery 297 patients were operated with coronary heart disease, acquired and congenital cardiac diseases and others. The introduction of principles of bloodless surgery is favoured by not only risk from donor transfusion, but also by the results of the reserchers dealing with the body's adaptation to acute anemia. The present study was undertaken to make a scientific-and-practical assessment of actual own blood funds and their introduction in order to decrease or refuse to use donor blood at cardiac surgery under extracorporeal circulation. Own blood saving methods, such as acute normovolemic hemodilution, washed autoerythrocytic reinfusion, autoplasma reinfusion, become affective in reducing hemorrhage after extracorporeal circulation. This method is safe, simple in organization, and permitted to avoid allogeneic blood transfusion and its complications.

The original method using for anastomosis formation between lymphatic node's subcapsular sinus and nearlying subcutaneous vein allows to cure or to achieve constant prevention of soft tissue lymphatic edema progress at extremities.

In 1934 Finder announced about 25 cases of discoid external intraarticuler cartilages of genus. Normally the menisci have a mesodermal development and differentiate from mesenchimal cells. In the aetiology of discoid meniscus are presented several theories. Discoid meniscus can be a disturbtion purpose for the patient. The frequency of discoid meniscus if high in the Asia. In some cases needs the operative treatment of discoid meniscus.

The study involved 237 patients aged 54 to 69 years who underwent aorto-bifemoral bypass surgery due to the atherosclerosis of aorta and its branches. Depending on a method of the anesthesia, patients were divided into 3 groups: in 1st group NLA was used, in the 2nd - epidural anesthesia at ThXII-LI with mechanical ventilation and in the 3rd - thoracic epidural anesthesia at ThX-ThXI with mechanical ventilation. The patient groups were representative. The most high and stable rates of coronary blood flow and central hemodynamics were in patients with thoracic epidural anesthesia (ThX-ThXI) with mechanical ventilation, due to the small doses of local anesthetic combined with a narcotic analgesic. Blockade of the sympathetic trunk has provided the most high and stable parameters of coronary flow, stroke output index and cardiac output fraction compared with other groups of patients.

Aim: to determine influence of genetic polymorphisms of hepatitis C virus and single nucleotide polymorphisms (SNPs) of patients with chronic hepatitis C on achieving sustained virological response (SVR) to antiviral therapy. One hundred blood samples of eastern-Slavonic patients with different response to the therapy were analyzed. It was determined, that among SNPs of 7 human genes only allelic variants of IL-1β, IL-28B, TGF-β1 and viral genotypes can influence on probability to achieve SVR.

In this study, 133 patients were divided by age into three groups. First group: from 17 to 29 years old; second group: from 30 to 49 years old; and third group: from 50 to 75 years old. Pain intensity of patients was measured by means of a Visual Analogue Scale (VAS), of a Numeric Rating Scale (NRS) and of a Verbal Lightning Scale (LS). All three scales could be used in measurement of pain of patients of the first group whereas NRS is preferable for the second group and LS - for the third group.

Aim: to study the influence of plasmapheresis, ultraviolet blood irradiation and their combination on the immunity indices. 142 patients with the progressive stage of extensive psoriasis from the age of 18 to 67 have been investigated. Indices of phagocytosis, cellular and humoral immunity have been studied in dynamics. Elevated levels of immunoglobulin M and A, circulating immune complexes, an imbalance of T-cell immunity as well as increasing neutrophil activity level of protection were revealed. The inclusion of the efferent-quantum methods in the complex treatment of psoriasis contributes to the normalization of T-lymphocyte subpopulations and the absorptive activity of neutrophils, reducing the CEC, immunoglobulin M and A. Better immunological efficacy noted when plasmapheresis and plasmapheresis were used in combination with ultraviolet blood irradiation.

The use of acetylsalicylic acid as antiaggregant is the standard antithrombotic therapy for secondary prevention in patients with myocardial infarction. But the methods of monitoring and analysis of cause of variable efficiency of this therapy is not currently specified. The purpose of this study was to evaluate platelet aggregation activity in patients with myocardial infarction and analysis of the causes of aggregation aspirin resistance. We examined 79 patients after myocardial infarction receiving aspirin. Presented the characteristics of aggregation curves corresponding to an effective antiplatelet therapy. It was revealed that the development of aggregation aspirin resistance depends on the presence of concomitant diseases, as well as receiving beta-blockers and diuretics, and does not depend on the concentration of platelets and acetylsalicylic acid in the blood.

The study presents the results of the analysis of domiciliary deaths of the population of a municipal polyclinic in Ufa in the dynamics between 2001 and 2010. The differences in the structure of mortality to the cause of death and sex between working-age population and pensioners were revealed. In ten years increased mortality from digestive system diseases (2,1 times) and malignant tumors (11,5%) was registered. For 2010 the mean age of the dead by months, days and time of death was detected. The obtained results were used as a basis for administrative decision making.

Manifested antibacterial action of copper nanoparticles on polyantibioticoresistant clinical strains of bacteria in the concentrations 0,001-1 mg/ml and in different temporary expositions has been determined. High antibacterial activity of copper nanoparticles has been revealed.