No 1 (2013)

A comparative study of the bacteria survival in water decontaminated by various physical methods is conducted.

This study presents the genetic polymorphism of HLA-antigens in acquired aplastic anemia (AAA) in 147 children (85 boys и 62 girls) aged 1 to 18 with. The control group is consisted of 1700 umbilical cord blood samples of healthy newborns. The genetic polymorphism of HLA was studied in groups of children with AAA, divided by gender and age. Our results revealed distinction in HLA-markers of predisposition and sustainability to AAA. Possible differences in factors of immunogenetic predisposition suggest different mechanisms involved in the development of the disease in different groups of children and reconsider the existing model of the pathogenesis of AAA.

ABPM records from 26 clinically healthy residents of Tosa City, Japan over 6 or 7 days were analyzed overall and day-by-day in order to determine the frequency of occurrence of vascular variability abnormalities (VVAs) and the extent of reproducibility of the results from one day to another. ABPM records over 18 to 33 hours from 360 patients of a specialized cardiology clinic in Almaty (Kazakhstan) with cardiovascular diseases of medium or high severity were also analyzed. Among all records from Tosa City, at least one VVA was found on at least one day in all residents. Twelve subjects with no overall abnormality had VVAs in 1 to 3 days. Of the remaining 14 subjects, only one had no overall abnormality but at least one VVA in 6 of 7 days. The other 13 had at least one VVA in 4 or more days as well as an overall abnormal record One or more VVAs occurred in 78% of the cardiac patients in Almaty. More than one type of VVA was found in 50% of the patients. In 22% of cardiac patients no VVA was found, despite the fact that these patients had cardiovascular diseases. The large day-to-day variability in circadian characteristics of blood pressure and heart rate observed in Tosa City and the associated presence or absence of VVA(s) on a given day indicate the need to monitor for longer than 24 hours and to repeat the monitoring once a VVA is detected, until historically feasible lifelong monitoring can be implemented.

The authors carried out serological and biochemical testing of blood serum of undergone hemodialysis 434 patients with chronic renal failure and constantly living in Baku for determination of hepatitis B and C viral infections spreading and pathogenic peculiarities of theses infections course at such patients. It was demonstrated that frequency of these infections' serologic markers detection among above mentioned patients was significantly higher than analogous indexes at healthy inhabitants of Baku. Besides it was shown that at more than 2/ 3 of patients both infections coursed in pathogenetical variants which were not accompanied with appearance in the blood biochemical signs of liver dysfunction.

At the solution of problem of hernioplasty of the big and huge postoperative recurrent median hernias alternatively to alloprosthetics were offered various reconstructive autoplastic operations referred on restitution of rectus muscles in natural position with which they occupied before herniation. The series of similar operations is historically surveyed. The preference is given to operation of O. Ramirez which however has number of disadvantages: fragile bracing of medial edges of rectus muscles that leads to frequent recurrences; real danger of occurrence of pararectal hernias. It is shown that the combination of this operation with autodermoplasty promotes substantial improvement of results of treatment. Among 124 operated it is registered 2 (1,6 %) lethal outcomes (in the nearest postoperative period) and 5 (4,0 %) recidives, are taped in the remote terms.

The results of the reconstructive operations on biliary tracts due to corrosive strictures can’t be considered satisfactory. In 12—30% of cases scarring of biliodigestive anastomosis is reported. The original endoscopic remodeling technique through the “closed end” of the Roux-en-Y loop empty intestine is described.

The success of the surgery performed on the urinary tract, much depends on preventing scar-sclerotic complications in the postoperative period. In this regard, an important issue is to find a path genetically based methods to prevent the development of urinary tract strictures. After performing surgical procedures on the urinary tract of a complex drug therapy by Longidaza 3000 IU in combination with magnetic-laser therapy can reduce the development of sclerotic complications in 3 times, which reduces the number of repeat surgery, and can be recommended for use in clinical practice.

The article presents data on the effects of ovarian hormones on the development of congenital cervical ectopia in young nulliparous women. Found that the pathological course of pregnancy leads to changes in the fetoplacental system, and results in a decrease of estriol concentration and increase of progesterone protective compensatory levels.

The article deals with the results of study of patients with diagnosed recurrent depressive disorder. The diagnostic criteria, clinical manifestations, psychological and social aspects and possibilities of therapy of bipolar II disorder are discussed.

According to the survey of students of the Peoples' Friendship University of Russia (pfur), revealed that to improve the catering students, according to the students, the need for food organization in canteens, organizing conditions for preparing food in the hostels, organizing time for meals at lunch time, the introduction of the post of a dietarian and a gastroenterologist at the PFUR clinic № 25. Required health education to students on the issue of the rational nutrition and a healthy lifestyle, which can be implemented in a variety of ways.