No 3 (2016)

We investigated the distribution of the AGT T174M and AGTR1 A1166C polymorphisms, which predispose to cardiovascular diseases, among Algerians, Syrians and Russians from Central Russia. The genotypes were determined with the use ofallele-specific PCR. A significant difference between the studied samples was revealed in the T174M genotype distribution, whereas no significant difference was found in case of the A1166C polymorphism.

The paper describes formation of abnormal conditions with the use of alcohol in a laboratory experiment. The generally accepted experimental model are evaluated from the point of view of their suitability for oculographic studies of operator activity. Recommendations for the use of these methods in oculographic study are given.

Article deals with the problem of aggression against people with mental diseases and presents the results of anonymous questionnaire survey. The estimation of prevalence of different types of interfamilial aggression is presented. Noticed the importance of identifying episodes of domestic violence against persons with mental disorders in order to optimize treatment, rehabilitation, and social and legal measures.

Conducted quantitative light-optical study of structures of biopsy samples of myometrium taken from 5 primiparas aged 21-38 years with physiological contractile activity. It was shown that the smooth muscle cells had different affinity to toluidine blue and were conditionally divided into light, dark and intermediate cells. Estimated the following parameters: the number of smooth muscle cells on 1 mm2 of myometrium, the percentage ratio of each types of muscle cells and cellular diameters. All estimated components have had intergroup variations. Results of this research can be used for comparative analysis of the same parameters in women with pathological contractile activity.

The literature review presents the problem of treatment of intraarticular fractures of proximal tibia. Russian and foreign literature has been analyzed, statistical data on patients disability as the result of unsatisfactory outcomes of treatment of intraarticular fractures of proximal tibia have been presented. Indications, contraindications, advantages and disadvantages of proposed methods of treatment of fractures of proximal tibia are given.

The human right to health means that health services should be available to everyone. According to the literature data, the availability of medical services is associated with the level and quality of primary health care. As it was announced in 1978 at WHO conference - organization of primary health care is a key aspect of the health system. For the assessment of the health situation in Algeria, we analyzed data from the literature, the WHO data, and the results of studies in different institutions. Based on the WHO guidelines, Algeria had gradually and constantly developed primary health care facilities and trained medical staff. The assessment of progress is made on the health criteria of the population and the health development in Algeria: the crude death rate and infant mortality rate, population per medical institution and per doctor Health facilities at the primary health care system are represented by the polyclinics and the care units. The number of primary health facilities had grown rapidly during the last forty years, from 1402 to 5484 care units and from 106 to 1627 polyclinics; the number of available hospital’s beds has evolved from 43404 to 63212 beds, while the population increased from 16,370,000 to 39,500,000 inhabitants. During the same period, the number of inhabitants per clinic increased from 140,000 to 20,000 people. One care unit serves about 7,000 people, the number of inhabitants per doctor decreased from 6000 to 600 inhabitants. Population health criteria shows the decline in infant mortality from 80 per 1,000 in 1984 to 46.8 per 1,000 in 1990 due to special programs for maternal and child health care and the expanded vaccination. The average life expectancy of the inhabitants of Algeria in 2014 reached the level of 77.2 years.

This article presents the analysis the activity of mobile dental office as a form of work organization of dental services in the region. Increasing the availability and quality of dental services to the population of predominantly rural areas is possible with targeted systemic approach in the organization of the dental service. Improving the outbound dental care to the rural population is possible in the development of targeted programs providing dental care to the population of the region.

In the article there are results of the comparative analysis of dynamics and tendencies of main diseases incidence in children constantly living in the city districts characterizing by different quality of the atmospheric air. The research revealed that living in the territory highly polluted by vehicle exhaust gas results in significant increase in the sick rate in children and as well as in the incidence of neoplasm, disease of endocrine, nervous, genitourinary systems, diseases of the ear and mastoid process, diseases of the skin and subcutaneous tissue and diseases of digestive system.

Analyzed the incidence of viral hepatitis B in the population on the territory of the Samara region. Two age groups in the structure of morbidity were considered, the most common - hepatitis B. The ratio in the incidence of urban and rural population is shown. Comparative analysis of morbidity of urban and rural population compared with the average Russian indicators at the beginning and the end of reviewed period (2000-2014 yrs.) is given.

“The cost of illness” is a detailed index for assessing the socio-economic losses caused by illness and related disability and death in money terms. The indicator is used in a variety of tasks, including the prediction of the positive effect of the medical devices introduction planning of the complex of medical-diagnostic and preventive measures in the healthcare system. The authors discussed in detail the structure of containing cost of illness losses (costs) - direct, indirect and intangible, briefly describes the key techniques for assessing cost of illness. SWOT-analysis carried out in the paper proved that “strongs” and “opportunities” despite possible negative impact of the internal and external factors contribute to the successful use of the “cost of illness” indicator in a wide range of different applications. In an aspect of the problem the key indicators of the road transport situation in Russia are described and the comparison of some key performance indicators of road transport situation in the country and in the world was carried out. Using specific examples in the field of traffic injuries the expedieny of the effect of the cost of illness-consequence on the structure of the cost of illness-cause was shown. Based on the foregoing, the modification of the structure of “cost of illness” proposed, taking into account an additional element, which we called “additive” losses, determining the contribution of a disease or condition in the cost of the other, which is the root cause of it. In view of these results it was concluded that the economic “assessment of the cost” of various diseases in the context of their relationship is of interest both from a theoretical and applied perspectives, and deserves further detailed study.

Consultative and diagnostic department of Moscow Regional Perinatal Center, indications to the direction to it for examination consistently considered in the article. Characteristic of the spectrum of manipulations and specific diagnostic methods perfoming in the department is given. Established that for 2010-2015 years the number of colposcopy, biopsy cervical and endometrial, polypectomy was increased several times. In the perinatal center there is a high coverage of pregnant women with prenatal ultrasound screening, while more than 94% of cases has been held three times. The main contingent of pregnant women sent for consultation, were patients with placental insufficiency and threatened miscarriage. In the department for clarifying the diagnosis the state of the fetus was evaluated by CTG, ultrasound fetometry, doppler investigation of fetoplacental complex. When detect of blood flow disorders or fetal growth retardation, pregnant women are hospitalized in this day to the department of pathology pregnancy of the center.

The article describes peculiarities of providing dental care for disabled children in Russia and other countries. Identified problems confirming the relevance of the research. Revealed high incidence of dental diseases among disabled children and the absence of mechanism for implementation of legal norms in the Russian legislation for development and realization of preventive measures for disabled children.