Peculiarities of the course of bronchopulmonary dysplasia associated with microaspiration of gastric contents

Tracheobronchial aspirate (TBA) was tested for marker of micro-aspiration of gastric contents - pepsin followed by analysis of the incidence and clinical picture of the developed bronchopulmonary dysplasia (BPD) in patients with and without microaspiration. Found that in children with micro-aspiration the frequency and the severity of BPD in all degrees of gestational maturity was higher and increased in proportion to the activity of pepsin in the TBA and lower gestational age.

micro-aspiration, tracheobronchial aspirate, pepsin, extinction, bronchopulmonary dysplasia