Cytodenic characteristics of patients with brain tumors under treatment by verapamilum and ketamine in vitro

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  • Authors: Fedoronchuk TV1, Syatkin SP1, Frolov VA1, Gridina NY.2, Boltina IV3
  • Affiliations:
    1. Russian Peoples' Friendship University
    2. State Institution Institute of Neurosurgery NAMS of Ukraine
    3. L.I. Medvedya Institute of ecohygiene and toxycology HМ of Ukraine
  • Issue: No 3 (2012)
  • Pages: 5-11
  • Section: Articles
  • URL: http://journals.rudn.ru/medicine/article/view/3605
  • Cite item

Abstract


There are results of analyzing of cytogenetic characteristics of patients with brain tumors under treatment by Verapamilum and Ketamine in vitro. Under the Verapamilum action it was shown sure decreasing of the chromosome aberrations frequencies just like decreasing of the aneuploid and polyploid cells quantity in patient's malignant tumors. It also was shown the substantial reduction in aneuploid cells number among tests of patients with malignant tumors under Ketamine exposure. Patients with benign or malignant tumors had the very lowest magnitudes of multyaberratic cells amount and of the extent of aberratic cell injury under the Verapamilum influence.

About the authors

T V Fedoronchuk

Russian Peoples' Friendship University

Email: rudnvestnik@yandex.ru
Russian Peoples' Friendship University

S P Syatkin

Russian Peoples' Friendship University

Email: syata@mail.ru <mailto:syata@mail.ru>
Russian Peoples' Friendship University

V A Frolov

Russian Peoples' Friendship University

Email: rudnvestnik@yandex.ru
Russian Peoples' Friendship University

N Ya Gridina

State Institution Institute of Neurosurgery NAMS of Ukraine

State Institution Institute of Neurosurgery NAMS of Ukraine

I V Boltina

L.I. Medvedya Institute of ecohygiene and toxycology HМ of Ukraine

L.I. Medvedya Institute of ecohygiene and toxycology HМ of Ukraine

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Copyright (c) 2012 Федорончук Т.В., Сяткин С.П., Фролов В.А., Гридина Н.Я., Болтина И.В.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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