RUDN Journal of MedicineRUDN Journal of Medicine2313-02452313-0261Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)3605Cytodenic characteristics of patients with brain tumors under treatment by verapamilum and ketamine in vitroFedoronchukT VRussian Peoples' Friendship Universityrudnvestnik@yandex.ruSyatkinS PRussian Peoples' Friendship Universitysyata@mail.ru <mailto:syata@mail.ru>FrolovV ARussian Peoples' Friendship Universityrudnvestnik@yandex.ruGridinaN YaState Institution Institute of Neurosurgery NAMS of Ukraine-BoltinaI VL.I. Medvedya Institute of ecohygiene and toxycology HМ of Ukraine-Russian Peoples' Friendship UniversityState Institution Institute of Neurosurgery NAMS of UkraineL.I. Medvedya Institute of ecohygiene and toxycology HМ of Ukraine15032012351107092016Copyright © 2012,2012There are results of analyzing of cytogenetic characteristics of patients with brain tumors under treatment by Verapamilum and Ketamine in vitro. Under the Verapamilum action it was shown sure decreasing of the chromosome aberrations frequencies just like decreasing of the aneuploid and polyploid cells quantity in patient's malignant tumors. It also was shown the substantial reduction in aneuploid cells number among tests of patients with malignant tumors under Ketamine exposure. Patients with benign or malignant tumors had the very lowest magnitudes of multyaberratic cells amount and of the extent of aberratic cell injury under the Verapamilum influence.KetamineVerapamilumchromosome aberrationsaneuploid and polyploid cellsbrain tumorsкетаминверапамилаберрации хромосоманеуплоидные и полиплоидные клеткиопухоли головного мозга