New views of mildronate use for the prevention and correction of impairment of adaptive processes

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Abstract


Protective and normalizing mildronate action on the level of non enzyme kation proteins in the neurophils and contents of kateholamins in erythrocytes were revealed on the experimental model of the emotional-pain stress. The findings of numerous investigations demonstrate that positive effects of mildronate were connected not only with its metabolism-modifying action but with accumulated holinolike metabolites of karnitine and normalizing influence on the central parts of neuro-endocrine systems, which ensure its use with the aim of increasing of adaptation to the outer environmental factors as well at to the prolonged phycho-emotional overstrain.

About the authors

L V Logunova

Ryazan state medical university

Email: LVLogunova@mail.ru
Кафедра нормальной и топографической анатомии; Рязанский государственный медицинский университет; Ryazan state medical university

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Copyright (c) 2010 Логунова Л.В.

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