The influence citokines in relapses of purulently complications at the diabetic foots and opportunities immunokorection

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Abstract


Studying of influence citokines in relapses of purulently complications at patients with a diabetic foots will allow to understand their function in development of pathological process. At 35 patients investigated levels: IL-1b, IL-4, IL-6, IL-8, IL-10 and FNO-a, ИНФ-γ in day of operation, for 3, 5, 7, 11, 21-22 day. There is an stimulaition only IL-8 up to 182,75 pg/ml in the first day before operation - to growth up to 245,5 pg /ml by 5 day and with decrease to 40,09 pg /ml by 21-22 days. With the purpose immunomodulation used polioksidoni at 12 patients. The effect of a preparation was shown in stimulaition citokines. 12 operations keeping to foots are executed. Use polioksidoni treatment of relapses of purulently complications is recommended at a diabetic foots.

V A Kislyakov

The Astrakhan State Medical Academy

Email: somvoz@live.ru <mailto:somvoz@live.ru>
Кафедра общей хирургии; АГМА; The Astrakhan State Medical Academy

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Copyright (c) 2009 Кисляков В.А.

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