Thrombolytic therapy and cardiac free wall rupture in patients with acute myocardial infarction

Abstract


The possible connection between thrombolytic therapy (TT) and the risk of left ventricle free wall rupture (LVFWR) in patients with acute myocardial infarction with ST-elevation (STEMI) is the point of discussion. The purpose of the study is evaluation of lethal outcomes among patients with STEMI. The retrospective analysis of medical data, including autopsy reports was performed. All data were divided in two groups: 210 case reports without TT and 188 reports with TT performed. Obtained data demonstrate the evident prevalence of LVFWR among patients, treated with TT: 52,4% vs 20,0% independently of myocardial reperfusion achieved. The evaluation of LVFWR risk at concrete patient with STEMI is strongly recommended.

E M Zeltyn-Abramov

Moscow State University of Medicine and Dentistry

Кафедра терапии № 1Факультет последипломного образования; Московский государственный медико-стоматологический университет; Moscow State University of Medicine and Dentistry

A E Radzevitch

Moscow State University of Medicine and Dentistry

Кафедра терапии № 1Факультет последипломного образования; Московский государственный медико-стоматологический университет; Moscow State University of Medicine and Dentistry

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Copyright (c) 2009 Зелтынь-Абрамов Е.М., Радзевич А.Э.

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