Abstract
Purpose: to estimate the efficacy of citicolines (CDP-choline) for treatment of glaucomatous optic neuropathy. According to the Innovative Educational Program at the Moscow Clinical Hospital № 12 40 patients (66 eyes) with primary open-angle glaucoma (POAG) stage II-III with normalized intraocular pressure were treated by citicoline in a dose 500mg/day during 10 days. The control group consisted of 40 patients with POAG stage II-III receiving an effective hypotensive therapy. We have evaluated the effect of citicoline (CDP-choline) on visual function, morphometric characteristic of retina tomography, characterizing the optic disk, and perimetric indexes of the static automatic perimetry and have compared the dynamic of estimated characteristics with those before treatment. In the group of patients, receiving citicoline (CDP-choline), visual functions have increased and perimetric indices of the static automatic perimetry have improved. Inclusion of citicoline (CDP-choline) in the treatment regimen of glaucomatous optic neuropathy makes standard therapy more effective for most indicators.
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