INTEGRATED ASSESSMENT OF THE FUNCTIONAL STATE OF HEALTHY STUDENTS IN DEPENDENCE ON THE PHASE AND THE DURATION OF THE MENSTRUAL CYCLE
- Authors: Penzhoyan G.A.1, Kashina Y.V.1, Abyshkevich V.G.1, Pokrovsky V.M.1
-
Affiliations:
- Kuban State Medical University
- Issue: Vol 23, No 2 (2019)
- Pages: 141-146
- Section: OBSTETRICS AND GYNECOLOGY
- URL: https://journals.rudn.ru/medicine/article/view/21353
- DOI: https://doi.org/10.22363/2313-0245-2019-23-2-141-146
Cite item
Full Text
Abstract
Relevance: one of the causes of menstrual disorders are functional disorders associated with a violation of the central regulatory level.The aim: integratively assess the functional state of healthy girls, depending on the phase and duration of the menstrual cycle. Materials and methods: observations were performed on 65 practically healthy girls 18-19 years old with regular menstrual cycles. They conducted questionnaires, gynecological examinations, tests on functional diagnostics tests, ultrasound scanning of pelvic organs. To determine the phases of the menstrual cycle used the method of Ogin-Knaus, the onset of ovulation used a test for luteinizing hormone (strip tests of the brand Eviplan). The concentration in the blood of estradiol and progesterone was selectively determined. All subjects underwent a cardio-respiratory synchronism test. The parameters of the serous-respiratory synchronism determined the index of the regulatory-adaptive status, and according to it the regulatory-adaptive capabilities (functional state) were evaluated. Statistical analysis of the results of the study was carried out using the following programs: «STATISTICA 10» of «Stat Soft, Inc.». After establishing the normal distribution of the variant, significant differences were used in comparing the mean values in paired comparisons, taking the t-test of Student for p < 0.05. Results: in 35 people the duration of the menstrual cycle was 21-27 days. In the follicular phase, the regulatory-adaptive status index was 183.0 ± 0.4, which indicated a high regulatory adaptive capacity. In the luteal phase, respectively, 60.1 ± 0.3, - good regulatory adaptive capacity. In 30 watchers, the cycle was 28 to 32 days. In the follicular phase, the regulatory-adaptive status index was 156.5 ± 0.6. Regulatory adaptive capabilities were good. In the luteal phase, respectively, 52.4 ± 0.5 are good regulatory adaptive capacities. The conclusion: Regulatory adaptive opportunities for female students are greater in the follicular phase of the menstrual cycle than in the luteal cycle. Regulatory adaptive capacity is greater for a cycle of 21 to 27 days than for a cycle of 28 to 32 days.
About the authors
G. A. Penzhoyan
Kuban State Medical University
Author for correspondence.
Email: pga05@mail.ru
Krasnodar, Russia
Yu. V. Kashina
Kuban State Medical University
Email: pga05@mail.ru
Krasnodar, Russia
V. G. Abyshkevich
Kuban State Medical University
Email: pga05@mail.ru
Krasnodar, Russia
V. M. Pokrovsky
Kuban State Medical University
Email: pga05@mail.ru
Krasnodar, Russia
References
- Mumford S.L., Steiner A.Z., Pollack A.Z., Perkins N.J., Filiberto A.C., Albert P.S. et al. The utility of menstrual cycle length as an indicator of cumulative hormonal exposure. Journal of Clinical Endocrinology and Metabolism. 2012. V. 97. P. 1871-1879.
- Podzolkova N.M., Danshina V.A. Violations of the menstrual cycle in the reproductive period. Medical advice. 2014. № 9. C. 44-49.
- Ahrens K.A., Vladutiu C.J., Mumford S.L., Schliep K.C., Perkins N.J., Wactawski-Wende J., and Schisterman E.F. The effect of physical activity across the menstrual cycle on reproductive function. Ann Epidemiol. 2014. V. 24. № 2. P. 127-134.
- Kuznetsova I.V. Lack of ovarian function at different ages and methods for its non-hormonal correction. Obstetrics and gynecology. 2013. № 1. С. 94-100.
- Gollenberg A.L., Hediger M.L., Mumford S.L., Whitcomb B.W., Hovey K.M., Wactawski-Wende J., et al. Perceived stress and severity of perimenstrual symptoms: the BioCycle Study. J Womens Health (Larchmt). 2010. № 19. P. 959-967.
- Kollipaka R., Arounassalame B., Lakshminarayanan S. Does psychosocial stress influence menstrual abnormalities in medical students? J. Obstet Gynaecol. 2013 № 33. P. 489-493.
- Nazish Rafique and Mona H. Al-Sheikh Prevalence of menstrual problems and their association with psychological stress in young female students studying health sciences. Saudi Med J. 2018. V. 39. № 1. P. 67-73.
- Kuznetsova I.V., Burchakov D.I. Managing the menstrual cycle is a new concept of combined oral contraceptives. Obstetrics and gynecology. 2016. № 10. C. 132-137.
- Abubakirov V.S., Bogatyreva A.N., Mishieva Kh.A., Martazanova N.G., Lapina B.A. The effectiveness of the protocols of stimulation of ovarian function in different phases of the menstrual cycle in patients with reduced ovarian reserve. Obstetrics and gynecology. 2017. № 11. C. 78-83.
- Strowitzki T., Capp E., von Eye Corleta H. The degree of cycle irregularity correlates with the grade of endocrine and metabolic disorders in PCOS patients. Eur J Obstet Gynecol Reprod Biol. 2010. V. 149. P. 78-181.
- Xu X., Shi Y., Cui Y., Ma J., Che L., Chen Z.J. Endocrine and metabolic characteristics of polycystic ovary syndrome in Chinese women with different phenotypes. Clin Endocrinol. 2012. V. 76. P. 425-430.
- Mamedgasanov R.M., Abbasova L.K., Meshadieva S.E. Treatment of menstrual cycle disorders in women with metabolic syndrome. World of medicine and biology. 2016. V. 1. № 55. P. 62-66.
- Cunningham M., Gilkeson G. Estrogen receptors in immunity and autoimmunity. Clinical reviews in allergy & immunology. Clinical reviews in allergy & immunology. 2011. V. 40. № 1. P. 66-73.
- Oertelt-Prigione S. Immunology and the menstrual cycle. Autoimmunity reviews. 2012 May V. 11. № 6. P. 486-492.
- Evans J., Salamonsen L.A. Inflammation, leukocytes and menstruation. Reviews in Endocrine and Metabolic Disorders. 2012. V. 13. № 4. P. 277-288.
- Teixeira A.L.S., Júnior W.F., Moraes E.M., Alves H.B., Damasceno V., Dias M.R. Effects of Menstrual Cycle Phase on Resting Heart Rate in Healthy Women. Journal of Exercise Physiologyonline. 2012. V. 15. № 4. P. 47-54.
- Christina K.F.K., Medabala T., Patil P., Sayana S.B. A Comparative Study Of Cardiac Autonomic Function Tests During Different Phases Of Menstrual Cycle. International Journal of Health Sciences and Research. 2013. V. 3. № 6. P. 34-40.
- Tejinder Kaur Brar Effect of Different Phases of Menstrual Cycle on Heart Rate Variability (HRV). J Clin Diagn Res. 2015. V. 9. № 10, CC01-CC04.
- Kalsina V.V. The dynamics of the functional state of athletes in different phases of the ovarian-menstrual cycle. Issues of functional training in the sport of higher achievements. 2013. № 1. С. 51-60.
- Zhuravleva Yu.S., Radysh I.V. Features of the change in the functional state of the body of female students involved in recreational aerobics. Human Ecology. 2009. № 10. P. 30-35.
- WMA Declaration of Helsinki - Ethical Principles for Medical Research Involving Human Subjects, 2013.
- Pokrovsky V.M., Ponomarev V.V., Artyushkov V.V., Fomina E.V., Gritsenko S.F., Polishchuk S.V. A system for determining cardio-respiratory synchronism in humans. Patent No. 86860 dated September 20, 2009.
- Pokrovsky V.M. Cardio-respiratory - a method of quantitative integrative assessment of the regulatory and adaptive status (condition) of the organism. Krasnodar, 2010. 243 p.