Cover Page

Cite item


Surgical methods for the treatment of glaucoma are used when other treatments are not effective to maintain intraocular pressure under control. Regardless of the method of choice of surgical treatment of glaucoma, penetrating and non-penetrating surgical intervention violates the integrity of the eyeball and causes a variety of complications. Some of these complications can threaten the vision as a whole. To keep complications to a minimum, it is important to know how to prevent, recognize and treat. One of the main problems of glaucoma surgery is scarring of the previously established ways of outflow of the experiences of all the researchers, who today are in search of new methods of prevention, means and methods for modulation of the process of excessive fibrosis of granulation tissue in the area of operations. The purpose of this article is to give an idea of some of the complications, advantages and disadvantages of the main methods of penetrating and non-penetrating surgical treatment, the use of different types of drains and the creation of new ways of outflow of intraocular fluid, which will help doctors in the future to improve the chosen techniques in the treatment of glaucoma patients in their clinical practice and to develop new methods against early scarring created outflow pathways and the extension of the hypotensive effect after surgery glaucoma.

About the authors

M A Frolov

Peoples’ Friendship University of Russia

SPIN-code: 1697-6960

A V Ryabey

Peoples’ Friendship University of Russia

Author for correspondence.
SPIN-code: 8447-8762

PhD Student, Department of Eye Diseases, Peoples' Friendship University of Russia

117198, ul. Miklukho-Maklaya, 6, Moscow, Russia

A M Frolov

Peoples’ Friendship University of Russia

SPIN-code: 6338-9946


  1. Balashova L.M. Immunohemostatic mechanisms in the development of primary open-angle glaucoma. Vestnik Oftalmologies 1997; 113(2):42—44. (In Eng.).
  2. Aspirant O.A. Comparative effectiveness of conservative and surgical methods for the treatment of primary open-angle glaucoma on blood supply of the optic nerve and retina. Vestn. ophthalmologies. 2001. T. 117. No. 4. P. 44—46.
  3. Akhmetshin R.F. Long-term results of surgical treatment of initial stage of primary open-angle glaucoma. Klinich. ophthalmology. 2002. Vol. 3. No. 2. P. 88—89.
  4. Nesterov A.P. Glaucoma. M.: Medicine, 1995. P. 186—225.
  5. Bessmertniy A.M. System of differentiated surgical treatment of refractory glaucoma: Dis.. Dr. med. Sciences / The Moscow research Institute of eye diseases. Helmholtz’s. M., 2006. P. 180—196.
  6. Hirschberg J. The History of Ophthalmology. J. P. Wayenborgh. 1994. 185 p.
  7. Wecker L. Sclerotomie simple et combine. Ann. d’ocul. 1894. Vol. 25. Р. 112.
  8. Herbert H. The Operative Treatment of Glaucoma. New York: William Wood. 1923. 152 p.
  9. Lagrange F. Iridectomie et sclerectomie dans le treatment du glaucoma chronique. Arch. d’ ophthalmol. 1906. Vol. 26. P. 481—496.
  10. Hoffmann-Egg L. Sympathetic ophthalmia after iridencleisis with extensive cell accumulation over the retinal vessels. Ophthalmologica. 1952. Vol. 123. P. 207—211.
  11. Harris D. Sympathetic ophthalmia following iridencleisis. Case report and incidence. Am. J. Ophthalmol. 1961. Vol. 51. P. 829—31.
  12. Elliot R.H. Preliminary note on a new operative procedure for the establishment of a filtering cicatrix in the treatment of glaucoma. Ophthalmoscope. 1909. Vol. 7. P. 804.
  13. Filatov V.P. In search of new principles to ensure fistulization anterior chamber in glaucoma. Soviet journal of ophthalmology. 1934. Vol. 4. Issus 2. P. 215—221.
  14. Filatov V.P., Kalfa S.F. Operations in glaucoma. In the book: Multipart guide eye diseases. Vol. 5. Medgiz, 1960. P. 108—173.
  15. Cairns J.E. Trabeculectomy. Preliminary report of a new method. Am. J. Ophthalmol. 1963. Vol. 66. No. 4. P. 673—679.
  16. Krasnov M.M. Glaucoma microsurgery. M.: Medicine, 1980. 248 p.
  17. Krasnov M.M. Pathogenic forms of glaucoma and principles of their surgical treatment]. Ophthalmologies. 1965. No. 5. P. 29—35.
  18. Bolgov P.Y. On the operations of Cioccaro glaucoma, Vestn. Oftalmol. 1945. Vol. 24. № 1—2. P. 77—83.
  19. Odintsov V.P. Operation in glaucoma. In the book. Guide eye surgery. Ed. by V.P. Odintsov and K.H. Orlov. M., 1934. Vol. 2. S. 693—794.
  20. Anwar M. Modifications of Scheie's operation. Br. J. Ophthalmol. 1970. Vol. 54. No. 4. P. 269—272.
  21. Heine L. Zur Therapie des Glaukoms. Erfahrungen mit der Zyklodialyse. Bericht d. 32. Versamml. d. ophthalmologischen Gesellschaft zu Heidelberg. Wiesbaden, 1905. P. 3—24.
  22. Nesterov A.P. Glaucoma. M.: Medicine, 1995. 255 с.
  23. Volik S.A., Volik E.I. The Effectiveness of deep sclerectomy in the surgical treatment of refractory glaucoma. Russian national ophthalmologic forum. M., 2012. T. 1. P. 35—39.
  24. Barashkov V.I., Dushin N.V., Belyaev V.S. et al. Sinusotrabeculactomy with adjustable filtration in the treatment of secondary glaucoma. Vestn. Oftalmol. 1999. No. 4. P. 7—11.
  25. Petrov S.Y. Trabeculectomy: practical tips. Methodical manual. M., 2013. 39 p.
  26. Watson P.G., Jakeman, C., Ozturk M. The complication of trabeculectomy (a 20-year follow-up). Eye. 1990. Vol. 4. No. 3. P. 425—438.
  27. Chen T.C., Wilensky J.T., Viana M.A. Long-term follow-up of initially successful trabeculectomy. Ophthalmology. 1997. Vol. 104. No. 7. P. 1120—1125.
  28. Hondrubia F.M., Grijalbo P., Gomez L., Tamargo D. A long-term study of trabeculectomy. J. Glaucoma. 1983. Vol. 5. No. 6. P. 284—288.
  29. Alekseev V.N. Complications and causes of failure of antiglaucomatous operations: Dis.. d-ra med. sciences'. M., 1988. 431 p.
  30. Babushkin A.E. Optimization of the hypotensive effect of trabeculectomy in open-angle glaucoma: abstract of Thesis. kand. honey. sciences'. M., 1988. 156 p.
  31. Petrov S.Yu., Podgorny N.N., Aslamazov A.E. Ciliochoroidal detachment. National journal of glaucoma. 2015. T. 14. No. 1. P. 94—102.
  32. Petrov S.Yu., Safonov D.M. The Modern concept of excess scarring in glaucoma surgery. Ophthalmology. 2015. Vol. 12. No. 4. P. 9—17.
  33. Picht G., Mutsch Y., Grehn F. Nachbetreuung von trabeculectomien. Komplikationen und therapeutische konsequenzen. Ophthalmologe. 2001. Vol. 98. No. 7. P. 629—634.
  34. Fedorov S.N., Kozlov V.I., Timoshkina N.T. et al. Non-Penetrating deep sclerectomy in open-angle glaucoma. Ophthalmic surgery. 1989. No. 3—4. P. 52—55.
  35. Lebedev O.I., Yavorsky A.E. To the question of the effectiveness of non-penetrating deep sclerectomy. Proc. scientific. articles scientific. scient. Conf. “Glaucoma: reality and perspectives”. M., 2008. P. 324—328.
  36. Shmyrev V.F., Petrov S.Yu., Malinin D.E. Combined operation epistolaire type in primary open angle glaucoma. Proc. early scientific articles. scient. Conf. “Glaucoma: reality and perspectives”. M., 2008. P. 359—363.
  37. Cheng J.W., Xi G.L., Wei R.L. et al. Efficacy and tolerability of nonpenetrating filtering surgery in the treatment of open-angle glaucoma: a meta-analysis. Ophthalmologica. 2010. Vol. 224. No. 3. P. 138—146.
  38. Gupalo O.D., Slonimsky S., Kulik A.V. Comparative analysis of remote results of repeated antiglaucomnah operations. Glaucoma. 2011. No. 1. S. 19—22.
  39. Takhchidi E.Kh., Kozlov N.A. Selection of an additional intervention on the eyes with decompensation of IOP at different times after microinvasive non-penetrating deep sclerectomy. Proc. proc. IX all-Russia. scientific. scient. Conf. with inter. participation “Fedorov readings—2011”. M., 2011. P. 349—350.
  40. Petrov S.Yu. Neparvarama the Efficiency of antiglaucomatous operations in primary open-angle glaucoma: abstract of thesis.kand. honey. sciences. M., 2004. 24 p.
  41. Lebedev O.I., Jaworski A.E., Stolyarov G.M. et al. Prevention of excessive scarring with non-penetrating deep sclerectomy. Glaucoma. 2011. No. 1. P. 32—36.
  42. Sorokin E.L., Abdullin Y.I. Combined non-penetrating deep sclerectomy with ultrasonic activation of the trabecular membrane in patients with trabecular-level retention in primary open angle glaucoma. Mater. scientific. scient. Conf. “Actual problems of ophthalmology”. Ufa, 2009. P. 455—457.
  43. Shmyrev V.F., Petrov S.Yu., Malinin D.E. Combined operation epistolaire type in primary open angle glaucoma. Proc. early scientific articles. scient. Conf. “Glaucoma: reality and perspectives”. M., 2008. P. 359—363.
  44. Cheglakov V.Y., Ivanova E.C. Microinvasive non-penetrating deep sclerectomy with implantation of a membranous drainage in patients with open-angle operated glaucoma. SB. proc. IX all-Russia. scientific. scient. Conf. with int. part “Fedorovskie readings—2011”. M., 2011. P. 357—357.
  45. Prokofiev M.I. Modern surgical approaches to treatment of refractory glaucoma (literature Review). Clinical ophthalmology. 2010. Vol. 3. No. 11. P. 104—108.
  46. Egorov E.A., Astakhov Yu.S., Erichev V.P. National guidance on glaucoma. Moscow, 2015. 452 s.
  47. Dushina G.N. Study of the effectiveness of segmental dilatatie sclera sinus canal in surgical treatment of open-angle glaucoma: abstract of thesis. Dis. Cand. med. sciences'. M., 2017.
  48. Murata M. An experimental study of the outflow pathway of the agueous humor after glaucoma surgery. Acta Soc. Ophthalmol. Jap. 1980. Vol. 84. No. 9. P. 329—335, 246—259.
  49. Krasnov M.M., Musaev P.I., Ziangirova G.G. Formation of intrascleral drainage tubules with transplant lens capsule. Vestn. oftalmol. 1987;6:6—11.
  50. Smirnov V.P., Zaikova M.V. A Modified deep sclerectomy with allodinia in open-angle glaucoma. Ophthalmic surgery 1995; 1:22—24.
  51. Frolov M.A., Lipatov D.V., Frolov A.M., Kazakova K.A. Combined method of surgical treatment of glaucoma in combination with cataract by the method of activation of uveoscleral path with autosclera. Point of view. East-West. No. 4, 2017.
  52. Frolov A.M. Combined method of surgical treatment of glaucoma in combination with cataract by the method of activation of uveoscleral path of Autoscroll: author. PhD. Thesis. M., 2017.

Copyright (c) 2018 Frolov M.A., Ryabey A.V., Frolov A.M.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies