Cover Page

Cite item


Pulmonary hypertension and pulmonary heart are severe complications of broncho-pulmonary dysplasia, accompanied by poor prognosis and high mortality. Based on Doppler echocardio-graphy in 100 children with bronchopulmonary dysplasia, the frequency of pulmonary hypertension de-velopment and pulmonary heart formation was determined. The risk factors for these complications and mortality outcomes have been defined. The quantitative evaluation of the informative value of electro-cardiographic, radiographic, computer tomographic signs of pulmonary hypertension in children with bronchopulmonary dysplasia was performed. The correspondence of the functional classes of pulmonary hypertension in the Panamanian classification of hypertensive vascular lung disease in children (2011) to the degree of increase in systolic pressure in the pulmonary artery and the severity of hypoxemia was defined.

About the authors

E A Degtyareva

RUDN University, Moscow, Russia; Childrens Infectious Diseases Hospital No. 6, Moscow, Russia

Author for correspondence.
Email: konovalov_oe@rudn.university
117198, Москва, ул. Миклухо-Маклая, 8

D Yu Ovsyannikov

RUDN University, Moscow, Russia; Childrens Infectious Diseases Hospital No. 6, Moscow, Russia

Email: mdovsyannikov@yahoo.com

доктор медицинских наук, зав. каф. педиатрии Российского университета дружбы народов.

117198, Москва, ул. Миклухо-Маклая, 8

N O Zaitseva

Childrens Infectious Diseases Hospital No. 6, Moscow, Russia

Email: konovalov_oe@rudn.university

A A Shokin

Childrens Infectious Diseases Hospital No. 6, Moscow, Russia

Email: konovalov_oe@rudn.university


  1. Northway W.H.Jr., Rosan R.C. & Porter D.Y. Pulmonary disease following respiratory therapy of hyaline membrane disease. Bronchopulmonary dysplasia. N Engl J Med. 1967. V. 276. N 7. P. 357—368.
  2. Zarqa A., Schmidt P., Dodd J. & Jeppesen D.L. Predictors of bronchopulmonary dysplasia and pulmonary hypertension in newborn children. Dan Med J. 2013. V. 60. N 8. P. 4688.
  3. Slaughter J.R., Pakrashi T., Jones D.E. et al. Echocardiographic detection of pulmonary hyperten-sion in extremely low birth weight infants with bronchopulmonary dysplasia requiring prolonged positive pressure ventilation. J Perinatol. 2011. N 10. P. 35—40.
  4. Gewitz M.H. Cor pulmonale — Pulmonary heart disease. In: Emmanoulides G.C., Allen H.D., Riemenschneider T.A. & Gutgesel H.P. (eds): Moss and Adams’Heart Disease in Infants, Child¬ren and Adolescents, Icluding the Fetus and Young Adult, 5th ed. Baltimore, Williams & Wilkins, 1994: 345—68.
  5. Ovsyannikov D.Yu., Komleva N.A., Oboladze T.B. et al. Modern Algorithms for Diagnostics of Bronchopulmonary Dysplasia. Pediatric Diagnostics. 2011. V. 3. N 1. P. 12—20.
  6. Subhedar N.V. & Shaw N.J. Changes in pulmonary arterial pressure in preterm infants with chronic lung disease. Arch Dis Child Fetal Neonatal Ed. 2000. V. 82. N 3. P. F243—F247.
  7. Fouron J.C., Le Guennec J.C., Villemant D. et al. Value of echocardiography in assessing the out-come of bronchopulmonary dysplasia of the newborn. Pediatrics. 1980. V. 65. N 3. P. 529—535.
  8. Khemani E., McElhinney D.B., Rhein L. et al. Pulmonary artery hypertension in formerly prema-ture infants with bronchopulmonary dysplasia: clinical features and outcomes in the surfactant era. Pediatrics. 2007. V. 120. N 6. P. 1260—1269.
  9. Schert R.F. & Park S.A. Complications in infants with bronchopulmonary dysplasia. In Bron¬chopulmonary dysplasia: Strategies for Total Patient Care. Ed. by C.H. Lund. 1989. P. 48—73.
  10. Abman S.H. Approach to the child with pulmonary hypertension and bronchopulmonary dys¬plasia. Advances in pulmonary hypertension. 2011. V. 10. N 2. P. 98—103.
  11. Abman S.H. Monitoring cardiovascular function in infants with chronic lung disease of pre¬maturity. Arch. Dis. Child. Fetal. Neonatol. Ed. 2002. P. 87: F15.
  12. Cerro M.J., Abman S., Diaz G. et al. A consensus approach to the classification of pediatric pul¬monary hypertensive vascular disease: Report from the PVRI Pediatric Taskforce, Panama 2011. Pulm Circ. 2011. V. 1. N 2. P. 286—298.
  13. Young T. & Mangum B. Neofax 2006. M.: Vereteya. 2006. 332 p.
  14. Mourani P.M., Sontag M.K., Dunbar Ivy D. et al. Effects of Long-term Sildenafil Treatment for Pulmonary Hypertension in Infants with Chronic Lung Disease. J Pediatr. 2009. V. 154. N 3. P. 379—384.
  15. Classification of clinical forms of bronchopulmonary diseases in children. M., Russian Respiratory Society, 2009.
  16. Greenough A., Kavvadia K., Johnson A.H. et al. A new simple chest radiograph score to predict chronic lung disease in prematurely born infants. British J. Radiol. 1999. N 72. P. 530—533.
  17. Edwards D.K. Radiographic aspects of bronchopulmonary dysplasia. J. Pediatr. 1979. N 95. P. 823—829.
  18. Galie N., Hoeper M. & Humbert M. Guidelines for the diagnosis and treatment of pulmonary hy-pertension. European Heart Journal. 2009. V. 30. N 20. P. 2493—2537.
  19. Barst R.J, McGoon M., Torbicki A. et al. Diagnosis and differential assessment of pulmonary arte-rial hypertension. JACC. 2004. N 12. 40S—47S.
  20. Hansen A.R., Barnes C.M., Folkman J. & McElrath T.F. Maternal preeclampsia predicts the de-velopment of bronchopulmonary dysplasia. J Pediatr. 2010. N 156. P. 532—536.

Copyright (c) 2017 Degtyareva E.A., Ovsyannikov D.Y., Zaitseva N.O., Shokin A.A.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies