Significance of the focal brain lesion in development of vestibular and acoustical disturbances in patients with multiple sclerosis

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Abstract


We have examined 72 patients aged from 18 till 62 with cerebral and cerebrospinal multiple sclerosis (MS) form. All patients have been underwent оtoneurologiс examination, electronystagmography (ENG), caloric tests, pure-tone audiometry, high frequency audiometry up to 20 kHz, impedance audiometry, auditory brainstem responses (ABR), magnetic resonance imaging (MRI). 59 patients had pathologically changed in MRI demyelination lesion in the brainstem. Demyelinization of the brainstem affects acoustical and vestibular function in patients with multiple sclerosis. Pathological changes of pure-tone audiometry, high frequency audiometry, acoustic reflexes and ABR may be regarded as subclinical signs of demyelinization of the cochleovestibular analyzer.

I M Kirichenko

the City hospital of Moscow № 4

Email: loririna@yandex.ru
ЛОР-отделение Городской клинической больницы № 4; the City hospital of Moscow № 4

V I Popaduk

Peoples' Friendship University of Russia

Email: EfimochkinaK@yandex.ru <mailto:EfimochkinaK@yandex.ru>
Кафедра оториноларингологии; Российский университет дружбы народов; Peoples' Friendship University of Russia

N A Dayhes

State Scientific Clinical Centre of ENT

State Scientific Clinical Centre of ENT

N S Alekseeva

Scientific Centre of the Neurology of RAMS

Scientific Centre of the Neurology of RAMS

N Sh Arzumanyan

Scientific Centre of the Neurology of RAMS

Scientific Centre of the Neurology of RAMS

A M Klochkov

The Russian State Medical University

Курс оториноларингологиифакультета усовершенствования врачей; РГМУ Росздрава; The Russian State Medical University

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Copyright (c) 2011 Кириченко И.М., Попадюк В.И., Дайхес Н.А., Алексеева Н.С., Арзуманян Н.Ш., Клочков А.М.

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