Change in time of spectral characteristics of drug substances (nir region)

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Abstract


The changes in NIR spectra of substances resulting from the processes of natural aging were investigated. The method of discriminant analysis was used for statistical evaluation of differences between two groups of spectra - for initial and aged substances. The values obtained for the spectral range of each substance can limit the possible dispersion of the samples arisen during their aging.

T E Elizarova

Ananalytical laboratory Farmanalis

Email: t-elizarova@farmanaliz.ru <mailto:t-elizarova@farmanaliz.ru>
Ananalytical laboratory Farmanalis

M A Morozova

Peoples' Friendship University of Russia

Email: gor-mariya@yandex.ru <mailto:gor-mariya@yandex.ru>
Кафедра фармацевтической и токсикологической химии; Российский университет дружбы народов; Peoples' Friendship University of Russia

T V Pleteneva

Peoples' Friendship University of Russia

Email: tvplet@mail.ru <mailto:tvplet@mail.ru>
; Peoples' Friendship University of Russia

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Copyright (c) 2011 Елизарова Т.Е., Морозова М.А., Плетенева Т.В.

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