The screening of the compounds with antiaggregation activity among benzimidazole and xantine

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Abstract


Antiaggregation activity of first synthesized benzimidazole and xantine derivatives has been studied. Differences in impact of the compounds on blood coagulability have been shown. We have synthesized L-65, on active compound, that suppresses platelet aggregation and has an acetylsalicylate acid-like effect. The results obtained concerning the screening of bioactive substances are promising.

About the authors

G A Timirkhanova

Bashkirian State Medical University

Bashkirian State Medical University

А V Samorodov

Bashkirian State Medical University

Bashkirian State Medical University

Ye E Klyen

Bashkirian State Medical University

Bashkirian State Medical University

O Y Travnikov

Bashkirian State Medical University

Bashkirian State Medical University

D A Enikeyev

Bashkirian State Medical University

Bashkirian State Medical University

V А Katayev

Bashkirian State Medical University

Bashkirian State Medical University

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Copyright (c) 2008 Тимирханова В.Н., Самородов А.В., Клен Е.Э., Травников О.Ю., Еникеев Д.А., Катаев В.А.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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