The screening of the compounds with antiaggregation activity among benzimidazole and xantine

G A Timirkhanova; Тимирханова В Н; А V Samorodov; Самородов А В; Ye E Klyen; Клен Е Э; O Y Travnikov; Травников О Ю; D A Enikeyev; Еникеев Д А; V А Katayev; Катаев В А

The screening of the compounds with antiaggregation activity among benzimidazole and xantine

Authors: Timirkhanova GA¹, Samorodov АV¹, Klyen Y.E¹, Travnikov OY¹, Enikeyev DA¹, Katayev VА¹
Affiliations:
1. Bashkirian State Medical University
Issue: No 4 (2008)
Pages: 68-72
Section: Articles
URL: https://journals.rudn.ru/medicine/article/view/3230

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Abstract

Antiaggregation activity of first synthesized benzimidazole and xantine derivatives has been studied. Differences in impact of the compounds on blood coagulability have been shown. We have synthesized L-65, on active compound, that suppresses platelet aggregation and has an acetylsalicylate acid-like effect. The results obtained concerning the screening of bioactive substances are promising.