The role of matrix metalloproteinases and vascular grouth facrors in differentional diagnostic of prostate’s diseases

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Abstract

The aim of this study was to determine of TRF1, MMP-7, FLT-1, KDR and VEGF mRNA expression levels obtained from prostate biopsies samples of patients with benign prostatic hyperplasia, prostate cancer and healthy men without prostate pathology. It was demonstrated that detection of TRF1, FLT-1, KDR and MMP-7 expression levels correlations and TRF1/MMP-7 index was criteria of different way for different prostate neoplasm diagnostics.

About the authors

V P Avdoshin

Peoples' Friendship University of Russia

Email: Susya@kmail.ru
Department of urology and operative nephrology

S A Pulbere

Peoples' Friendship University of Russia

Email: pulpiv@mail.ru
Department of urology and operative nephrology

A V Loktev

Peoples' Friendship University of Russia

Email: doklok@mail.ru
Department of urology and operative nephrology

A I Glukhov

Moscow Research Institute of Medical Ecology

Email: pulpiv@mail.ru
Department of Health of Moscow

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Copyright (c) 2014 Авдошин В.П., Пульбере С.А., Локтев А.В., Глухов А.И.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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