Characteristics of the circadian profile of heart rate during genetically determined hypertension

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Abstract


Prevalence and importance of hypertension in the general incidence structure determines a wide range of research problems. Chronobiological indices are of great importance in the investigatory activity concerning mechanisms of essential hypertension. Our work was focused on the dynamics of HR circadian profile at different terms in male SHR rats with the use of telemetry monitoring. The obtained data showed considerable changes of cardiac rhythm in different time intervals which was understood as inhibition of the chronotropic function of the heart.

About the authors

V A Goryachev

Peoples' Friendship University of Russia

Email: forarmi@yandex.ru
Department of General Pathology and Pathological Physiology

M L Blagonravov

Peoples' Friendship University of Russia

Email: blagonravovm@mail.ru
Department of General Pathology and Pathological Physiology

M M Azova

Peoples' Friendship University of Russia

Email: forarmi@yandex.ru
Department of Biology and General Genetics

E V Velichko

Peoples' Friendship University of Russia

Email: forarmi@yandex.ru
Department of General Pathology and Pathological Physiology

E N Trukhina

Peoples' Friendship University of Russia

Email: forarmi@yandex.ru
Department of General Pathology and Pathological Physiology

V A Frolov

Peoples' Friendship University of Russia

Email: victorfro@rambler.ru
Department of General Pathology and Pathological Physiology

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Copyright (c) 2014 Горячев В.А., Благонравов М.Л., Азова М.М., Величко Э.В., Трухина Е.Н., Фролов В.А.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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