Oxidant-antioxidant status of erythrocytes in chronic obstructive pulmonary disease

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Abstract


In 70 patients with COPD studied mechanisms of oxidative stress on the changes in oxidant-antioxidant status of erythrocytes. Found that the intensity of oxidative stress in red blood cells is directly dependent on the severity of the disease. Maximum activity of antioxidant enzymes found in patients with secondary erythrocytosis with stage II disease. In patients with stage III COPD, oxidative stress was significantly expressed and is associated with a sharp fall in activity of antioxidant systems.

N A Mishina

Samara Medical University

Кафедра госпитальной терапии; Самарский государственный медицинский университет; Samara Medical University

I L Davydkin

Samara Medical University

Кафедра госпитальной терапии; Самарский государственный медицинский университет; Samara Medical University

V I Kupaev

Samara Medical University

Кафедра госпитальной терапии; Самарский государственный медицинский университет; Samara Medical University

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Copyright (c) 2010 Мишина Н.А., Давыдкин И.Л., Купаев В.И.

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