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Oxidant-antioxidant status of erythrocytes in chronic obstructive pulmonary disease
- Authors: Mishina NA1, Davydkin IL1, Kupaev VI1
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Affiliations:
- Samara Medical University
- Issue: No 4 (2010)
- Pages: 354-356
- Section: Articles
- URL: https://journals.rudn.ru/medicine/article/view/2796
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Abstract
In 70 patients with COPD studied mechanisms of oxidative stress on the changes in oxidant-antioxidant status of erythrocytes. Found that the intensity of oxidative stress in red blood cells is directly dependent on the severity of the disease. Maximum activity of antioxidant enzymes found in patients with secondary erythrocytosis with stage II disease. In patients with stage III COPD, oxidative stress was significantly expressed and is associated with a sharp fall in activity of antioxidant systems.
About the authors
N A Mishina
Samara Medical UniversityКафедра госпитальной терапии; Самарский государственный медицинский университет; Samara Medical University
I L Davydkin
Samara Medical UniversityКафедра госпитальной терапии; Самарский государственный медицинский университет; Samara Medical University
V I Kupaev
Samara Medical UniversityКафедра госпитальной терапии; Самарский государственный медицинский университет; Samara Medical University
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