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The role of opiates and K+ATP-channels of plasma and cell membranes mitohondrial kidneys in the development of apoptosis
- Authors: Komarevtseva IA1, Komarevtseva KV1, Belous YA2
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Affiliations:
- LGMU
- Peoples' Friendship University of Russia
- Issue: No 2 (2009)
- Pages: 83-88
- Section: Articles
- URL: https://journals.rudn.ru/medicine/article/view/3710
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Abstract
The study of researching is to examine the role of opiates and channels of plasma and mitochondrial membrane of kidney cells in the development of apoptosis.
In this experiment rats were used white-male mice of sixteen-eighteen weeks of age. Animals were formed renal tubular injury with help of two models - ischemic and «glitserolnoy» (intramuscular introduction of 50% solution of glitserol). Dalargin was injected 20 minutes before the renal tubular injury.
As a result of our established mechanism of action of opioids in the kidney cells.
In this experiment rats were used white-male mice of sixteen-eighteen weeks of age. Animals were formed renal tubular injury with help of two models - ischemic and «glitserolnoy» (intramuscular introduction of 50% solution of glitserol). Dalargin was injected 20 minutes before the renal tubular injury.
As a result of our established mechanism of action of opioids in the kidney cells.
Keywords
About the authors
I A Komarevtseva
LGMUКафедра медицинской химии; ЛГМУ; LGMU
K V Komarevtseva
LGMUКафедра медицинской химии; ЛГМУ; LGMU
Y A Belous
Peoples' Friendship University of RussiaКафедра психотерапии и наркологии ФПКМР; Российский университет дружбы народов; Peoples' Friendship University of Russia
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