Severity of systemic inflammatory response syndrome in the I trimester as a marker of late pregnancy complications

M G Gazazyan; Газазян М Г; N A Ponomareva; Пономарева Н А; I N Mazepkina; Мазепкина И Н; O U Ivanova; Иванова О Ю; I V Stepanenko; Степаненко И В

Severity of systemic inflammatory response syndrome in the I trimester as a marker of late pregnancy complications

Authors: Gazazyan MG¹, Ponomareva NA¹, Mazepkina IN¹, Ivanova OU¹, Stepanenko IV¹
Affiliations:
1. Kursk State Medical University
Issue: No S5 (2011)
Pages: 60-66
Section: Articles
URL: https://journals.rudn.ru/medicine/article/view/3379

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Abstract

A complex dynamic examination of 162 pregnant patients was carried out. The study revealed the link between severity of systemic inflammatory response syndrome in the I trimester and development of late pregnancy complications. Increased levels of proinflammatory cytokines, decreased phagocytic and functional activity of neutrophils and changes in correlation CD4/CD8 in the I trimester could serve as early markers of complicated pregnancy.