Pathomorphological aspects of the embriochorionic complex in the first trimester of pregnancy that complicated by insulin-dependent diabetes mellitus of various severity and stage of compensation

I A Burenkova; Буренкова И А; I M Ordiynts; Ордиянц И М; L R Burganova; Бурганова Л Р; F G Zabzolaev; Забзолаев Ф Г; T V Zlatovratskaya; Златовратская Т В; M A Sarmosyan; Сармосян М А

Pathomorphological aspects of the embriochorionic complex in the first trimester of pregnancy that complicated by insulin-dependent diabetes mellitus of various severity and stage of compensation

Authors: Burenkova IA¹, Ordiynts IM¹, Burganova LR¹, Zabzolaev FG², Zlatovratskaya TV³, Sarmosyan MA³
Affiliations:
1. Peoples Friendship University of Russia
2. Russian Medical Academy of Postgraduate Education
3. Clinical Hospital № 29
Issue: No S5 (2011)
Pages: 19-26
Section: Articles
URL: https://journals.rudn.ru/medicine/article/view/3373

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Abstract

The uterine-placental complex in insulin-dependent diabetes mellitus develops under conditions of preexisting angiopathy and chronic hyperglycemia, affecting its morphofunctional state. Inadequate gestational re-structuring of spiral arteries combined with villous-chorion dyschonia, thrombosis, and intervillous-space incompetence suggest early insufficiency of the embryonal system, thus being predictors of placental insufficiency developing in the second and third trimesters of pregnancy.