Correlation between cells blood aggregation and peripheral blood cells lymphocyte aberration in brain glioma patients

V A Frolov; Фролов Виктор Алексеевич; S P Syatkin; Сяткин Сергей Павлович; T V Fedoronchuk; Федорончук Тамара Васильевна; N Ya Gridina; Гридина Нина Яковлевна; I V Boltina; Болтина Ирина Владимировна; Yu V Ushenin; Ушенин Юрий Валентинович

Correlation between cells blood aggregation and peripheral blood cells lymphocyte aberration in brain glioma patients

Authors: Frolov VA¹, Syatkin SP¹, Fedoronchuk TV¹, Gridina NY.², Boltina IV³, Ushenin Y.V⁴
Affiliations:
1. Peoples' Friendship University of Russia
2. State Institution Institute of Neurosurgery NAMS of Ukraine
3. L.I. Medvedya Institute of ecohygiene and toxycology HМ of Ukraine
4. V.E. Lashkarev Institute of semiconducter physics NAS Ukraine
Issue: No 1 (2012)
Pages: 11-16
Section: Articles
URL: https://journals.rudn.ru/medicine/article/view/3295

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Abstract

The correlation between the peripheral blood cells aggregation level measured by surface plasmon resonance method (SPR), and chromosomal abberations of peripheral blood lymphocytes in brain malignant gliomas patients was investigated. It was found, that results of SPR in patients with brain gliomas were significantly lower than in healthy persons and gradually decreased with increasing of the gliomas malignancy grade. It was shown that decreasing of SPR data correlate with the statistically significant increase of chromosomal aberration in peripheral blood lymphocytes in glioma patients.

Keywords

blood cells aggregation, surface plasmon resonance method, chromosomal aberrations, brain malignant gliomas

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Vol 29, No 2 (2025): CARDIOLOGY

Correlation between cells blood aggregation and peripheral blood cells lymphocyte aberration in brain glioma patients

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About the authors

V A Frolov

S P Syatkin

T V Fedoronchuk

N Ya Gridina

I V Boltina

Yu V Ushenin

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