Exogenous serotonin potentiates vagal reaction of the colon

V I Torshin; Торшин Владимир Иванович; V M Smirnov; Смирнов Виктор Михайлович; D S Sveshnikov; Свешников Дмитрий Сергеевич; A V Kuchuk; Кучук Андрей Владимирович; I L Myasnikov; Мясников Игорь Леонидович

Exogenous serotonin potentiates vagal reaction of the colon

Authors: Torshin VI¹, Smirnov VM², Sveshnikov DS², Kuchuk AV², Myasnikov IL²
Affiliations:
1. Peoples' Friendship University of Russia
2. Russian State Medical University
Issue: No 1 (2012)
Pages: 5-10
Section: Articles
URL: https://journals.rudn.ru/medicine/article/view/3294

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Abstract

This study is dedicated to serotoninergic structures of the colon. Experiments were performed in 35 Chinchilla rabbits under general anesthesia, mechanical ventilation, bilateral vagotomy. Mechanical and electrical activity of the ascending colon was recorded during electrical stimulation of the peripheral part of the right n. vagi in intact animals and after serotonin adipate injection. It was found that serotonin potentiates vagal effects of the colon, but without effect on duration of reaction. Concluded that the serotoninergic structures of the colon are able to control the parasympathetic portion of the autonomic nervous system.

Keywords

serotoninergic structures, large intestine, the vagus nerve

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Vol 28, No 4 (2024): ONCOLOGY

Exogenous serotonin potentiates vagal reaction of the colon

Full Text

Abstract

Keywords

About the authors

V I Torshin

V M Smirnov

D S Sveshnikov

A V Kuchuk

I L Myasnikov

References

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