Laser techniques in the analysis of solutions synthetic peptides

E V Uspenskaya; Успенская Елена Валерьевна; T V Pleteneva; Плетенева Татьяна Вадимовна; T A Golubtsova; Голубцова Татьяна Андреевна; A Yu Skripnikov; Скрипников Александр Юрьевич; A V Syroeshkin; Сыроешкин Антон Владимирович

Laser techniques in the analysis of solutions synthetic peptides

Authors: Uspenskaya EV¹, Pleteneva TV¹, Golubtsova TA², Skripnikov AY.³, Syroeshkin AV⁴
Affiliations:
1. Peoples’ Friendship University of Russia
2. Testing Laboratory «Pharmconstant»
3. Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry Russian Academy of Sciences
4. Institute of Applied Geophysics
Issue: No 3 (2013)
Pages: 94-99
Section: Articles
URL: https://journals.rudn.ru/medicine/article/view/2712

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Abstract

The search for new drugs based on protein/peptide compounds is associated with the development of methods for quality control and standardization of pharmaceutical preparations. The physicochemical properties of solutions of peptides synthesized by the method of dynamic light scattering (DLS) are discussed. The dispersion distribution of peptide molecules in size and the number are described. The results can be used for qualitative evaluation of peptide drug solutions.