The studying of connection of molecular-genetic markers of interlakines with the clinical current chronic glomerulonephritis

E V Kalmykova; Калмыкова Е В; I S Polyakova; Полякова И С; K I Proschaev; Прощаев К И; V G Nesterov; Нестеров В Г; V S Vaschilin; Ващилин В С; M I Churnosov; Чурносов М И

The studying of connection of molecular-genetic markers of interlakines with the clinical current chronic glomerulonephritis

Authors: Kalmykova EV¹, Polyakova IS¹, Proschaev KI¹, Nesterov VG¹, Vaschilin VS¹, Churnosov MI¹
Affiliations:
1. BelSU
Issue: No 4 (2009)
Pages: 619-620
Section: Articles
URL: https://journals.rudn.ru/medicine/article/view/2585

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Abstract

The present research is devoted revealing of interrelations of genetic markers interleukines with clinical signs chronic glomerulonephritis. It is established that a marker of development of mixed type chronic glomerulonephritis at a disease aggravation are genotypes 4R/4R a gene of the antagonist of a receptor interleukin 1 and -592AA, -592AS gene IL-10. The positive association of genotypes 2R/5R, 4R/5R IL-1Ra with type chronic glomerulonephritis in a disease current is revealed.

Keywords

chronic glomerulonephritis, interleukins genes