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Effect of Long-Term Electrical Spinal Cord Stimulation on Expression of Non-Reciprocal Inhibition α-Motoneurons of Human Skeletal Muscles
- Authors: Roshchina L.V.1, Gladchenko D.A.1, Pivovarova E.A.1, Chelnokov A.A.1
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Affiliations:
- Velikie Luki State Academy of Physical Education and Sports
- Issue: Vol 23, No 4 (2019)
- Pages: 390-396
- Section: BIOLOGY. EXPERIMENTAL PHYSIOLOGY
- URL: https://journals.rudn.ru/medicine/article/view/22799
- DOI: https://doi.org/10.22363/2313-0245-2019-23-4-390-396
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Abstract
It is known, transcutaneous electrical spinal cord stimulation (tESCS) in the T11-T12 level of the thoracic vertebrae increases the power capabilities of the leg agonist muscles. One of the inhibition spinal mechanisms that protects skeletal muscles from excessive force is non-reciprocal inhibition. Taking into account the biological role of non-reciprocal inhibition, the aim of the study was to research the effect of long-term tESCS on expression of non-reciprocal inhibition of soleus muscle α-motorneurons in humans at rest and when holding a weak static force. Materials and methods: the study involved 22 healthy male subjects aged 27 to 35 years. Non-reciprocal inhibition of α-motorneurons was recorded during the 20-minute tESCS in the T11-T12 level of the thoracic vertebrae at rest, in combination with arbitrary muscular effort (5% of MVC) and after its impact. Results: TESCS at rest resulted in the weakening of non-reciprocal inhibition within 20 minutes of exposure and 10 minutes after the end of stimulation. TESCS in combination with arbitrary muscular effort in 5% of the MVC increases the activity of non-reciprocal inhibition for 20 minutes of stimulation and 10 minutes after its end. The proposed physiological mechanisms underlying the effect of long-term tESCS on expression of non-reciprocal inhibition are discussed.
About the authors
L. V. Roshchina
Velikie Luki State Academy of Physical Education and Sports
Author for correspondence.
Email: ljudaroschina@yandex.ru
Velikie Luki, Russian Federation
D. A. Gladchenko
Velikie Luki State Academy of Physical Education and Sports
Email: ljudaroschina@yandex.ru
Velikie Luki, Russian Federation
E. A. Pivovarova
Velikie Luki State Academy of Physical Education and Sports
Email: ljudaroschina@yandex.ru
Velikie Luki, Russian Federation
A. A. Chelnokov
Velikie Luki State Academy of Physical Education and Sports
Email: ljudaroschina@yandex.ru
Velikie Luki, Russian Federation
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