Interrelation of infringements of microflorae of vaginae and features of change of mechanisms of immunoreactiviti at women with adiposity

Abstract

We have examined 166 women in the age of 17 to 44 years old. 2 clinical groups were formed: the basic one was 96 women (IMB > 28 kg/ m2) and the control group of 70 women (IМB < 28 kg/m2). Bacteriological and immunological methods were applied while research. It is stated that women with IMB more than 28 kg/ml actually more often had nonspecific vaginitis, bacterial vaginosis, and ureaplasmas, representatives of intestinal group of microorganisms (Enterococcus, E. coli, Klebsiellа, Proteus). Also, women with IMB more than 28 kg/ml actually had higher level of C-peptid; and while making the correlation analysis high positive correlation dependence between a degree of adiposity and antibodies (IgM and IgА) and a degree of adiposity was revealed. Women with IMB more than 28 kg/ml and infringement of vaginas microflorae had 3 times more markers of system inflammatory reaction: C-peptid, IL-8, INF-γ.