Diagnosis aggregation aspirin resistance in patients after myocardial infarction in the secondary prevention of thrombotic complications

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Abstract


The use of acetylsalicylic acid as antiaggregant is the standard antithrombotic therapy for secondary prevention in patients with myocardial infarction. But the methods of monitoring and analysis of cause of variable efficiency of this therapy is not currently specified. The purpose of this study was to evaluate platelet aggregation activity in patients with myocardial infarction and analysis of the causes of aggregation aspirin resistance. We examined 79 patients after myocardial infarction receiving aspirin. Presented the characteristics of aggregation curves corresponding to an effective antiplatelet therapy. It was revealed that the development of aggregation aspirin resistance depends on the presence of concomitant diseases, as well as receiving beta-blockers and diuretics, and does not depend on the concentration of platelets and acetylsalicylic acid in the blood.

P P Ogurtsov

Peoples' Friendship University of Russia

Email: rudnvestnik@yandex.ru
Кафедра госпитальной терапиис курсом клинической лабораторной диагностики; Российский университет дружбы народов; Peoples' Friendship University of Russia

A G Kochetov

Peoples' Friendship University of Russia

Email: rudnvestnik@yandex.ru <mailto:rudnvestnik@yandex.ru>, kochetov.lab@mail.ru
Кафедра госпитальной терапиис курсом клинической лабораторной диагностики; Российский университет дружбы народов; Peoples' Friendship University of Russia

O V Lyang

Peoples' Friendship University of Russia

Email: rudnvestnik@yandex.ru
Кафедра госпитальной терапиис курсом клинической лабораторной диагностики; Российский университет дружбы народов; Peoples' Friendship University of Russia

R R Politidis

Peoples' Friendship University of Russia

Email: rudnvestnik@yandex.ru
Кафедра госпитальной терапиис курсом клинической лабораторной диагностики; Российский университет дружбы народов; Peoples' Friendship University of Russia

A D Djappuev

Peoples' Friendship University of Russia

Кафедра госпитальной терапиис курсом клинической лабораторной диагностики; Российский университет дружбы народов; Peoples' Friendship University of Russia

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Copyright (c) 2012 Огурцов П.П., Кочетов А.Г., Лянг О.В., Политидис Р.Р., Джаппуев А.Д.

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