Cytostatic disease and lipid peroxidation

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Abstract


We studied the state of LPO in the animals in experimental radiation sickness and cytostatic (cyclophosphamide and doxorubicin) disease. It is shown that the effect on the body of cytostatic factor activated LPO, increased level of MDA, decreased antioxidant enzyme activity. Last determines the feasibility of control LPO during chemotherapy and radiotherapy and adequate timely correction of lipid peroxidation during their activation.

About the authors

N I Mikulyak

Penza State Universiti

Email: somvoz@live.ru
Кафедра физиологии человека; Медицинский институт ПГУ; Penza State Universiti

A I Mikulyak

Penza State Universiti

Email: somvoz@live.ru
Кафедра физиологии человека; Медицинский институт ПГУ; Penza State Universiti

S A Goldhaur

Penza State Universiti

Email: somvoz@live.ru
Кафедра физиологии человека; Медицинский институт ПГУ; Penza State Universiti

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Copyright (c) 2009 Микуляк Н.И., Микуляк А.И., Гольдхаур С.А.

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