Claudin-1 and Ki-67 expression in oral leukoplakia and oral squamous cell carcinoma

A A Katushkina; Катушкина Анастасия Анатольевна; V A Koviazin; Ковязин В А; I I Babichenko; Бабиченко И И; A S Grigorian; Григорьян А С

Claudin-1 and Ki-67 expression in oral leukoplakia and oral squamous cell carcinoma

Authors: Katushkina AA¹, Koviazin VA¹, Babichenko II¹, Grigorian AS²
Affiliations:
1. Peoples' Friendship University of Russia
2. Central Research Institute for Stomatology
Issue: No 3 (2010)
Pages: 94-97
Section: Articles
URL: https://journals.rudn.ru/medicine/article/view/3515

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Abstract

The correlation was investigated between the level of cell proliferation and the intensity of claudin-1 expression in oral Leukoplakia with different grade of cell neoplastic transformation (according to WHO classification 2005, - SIN - Squamous Intraepithelial Neoplasia) and in oral Squamous cell carcinoma. Claudin-1 expression and cell proliferation were assessed using immunohistochemistry in different epithelial layers of oral mucosa. The inverse correlation was revealed between the level of cell proliferation and the intensity of claudin-1 expression in oral Leukoplakia and oral Squamous cell carcinoma.

Keywords

Ki-67, leukoplakia, squamous cell carcinoma, oral mucosa, Ki-67, claudin-1

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Vol 28, No 3 (2024): PHYSIOLOGY. EXPERIMENTAL PHYSIOLOGY

Claudin-1 and Ki-67 expression in oral leukoplakia and oral squamous cell carcinoma

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Abstract

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About the authors

A A Katushkina

V A Koviazin

I I Babichenko

A S Grigorian

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