Diagnosis aggregation aspirin resistance in patients after myocardial infarction in the secondary prevention of thrombotic complications

P P Ogurtsov; Огурцов Павел Петрович; A G Kochetov; Кочетов Анатолий Глебович; O V Lyang; Лянг Ольга Викторовна; R R Politidis; Политидис Рита Романовна; A D Djappuev; Джаппуев А Д

Diagnosis aggregation aspirin resistance in patients after myocardial infarction in the secondary prevention of thrombotic complications

Authors: Ogurtsov PP¹, Kochetov AG¹, Lyang OV¹, Politidis RR¹, Djappuev AD¹
Affiliations:
1. Peoples' Friendship University of Russia
Issue: No 2 (2012)
Pages: 116-121
Section: Articles
URL: https://journals.rudn.ru/medicine/article/view/3121

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Abstract

The use of acetylsalicylic acid as antiaggregant is the standard antithrombotic therapy for secondary prevention in patients with myocardial infarction. But the methods of monitoring and analysis of cause of variable efficiency of this therapy is not currently specified. The purpose of this study was to evaluate platelet aggregation activity in patients with myocardial infarction and analysis of the causes of aggregation aspirin resistance. We examined 79 patients after myocardial infarction receiving aspirin. Presented the characteristics of aggregation curves corresponding to an effective antiplatelet therapy. It was revealed that the development of aggregation aspirin resistance depends on the presence of concomitant diseases, as well as receiving beta-blockers and diuretics, and does not depend on the concentration of platelets and acetylsalicylic acid in the blood.

Keywords

aggregation, aspirin resistance, antiplatelet therapy

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Vol 28, No 3 (2024): PHYSIOLOGY. EXPERIMENTAL PHYSIOLOGY

Diagnosis aggregation aspirin resistance in patients after myocardial infarction in the secondary prevention of thrombotic complications

Full Text

Abstract

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About the authors

P P Ogurtsov

A G Kochetov

O V Lyang

R R Politidis

A D Djappuev

References

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