Directed search of hypoglycemic compounds in the series of aroylpyruvic acid derivatives

N A Pulina; Пулина Наталья Алексеевна; T A Yushkova; Юшкова Татьяна Александровна; A I Krasnova; Краснова Анастасия Ивановна; V V Yushkov; Юшков Владимир Викторович

Directed search of hypoglycemic compounds in the series of aroylpyruvic acid derivatives

Authors: Pulina NA¹, Yushkova TA¹, Krasnova AI¹, Yushkov VV¹
Affiliations:
1. Perm State Pharmaceutical Academy
Issue: No 4 (2010)
Pages: 423-425
Section: Articles
URL: https://journals.rudn.ru/medicine/article/view/2813

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Abstract

The article deals with synthesis of new oxovanadium metal complexes in the series of esters and arylamides of aroylpyruvic acids. Comparative estimation of hypoglycemic activity of original ligands and obtained chelates is conducted. The introduction of oxovanadium into molecule is found to potentiate sugar-reducing activity.