The immune modulators as geroprotectors: the cellular growth potential restoration of the old mice by means of the immune-modulator «Transfer-Factor»

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Abstract

Biologically active dietary supplement «Transfer-Factor», produced by «4 Life Research Co» (the USA) from cow beestings reestablishes the potential of cellular growth lowered within the processes of aging what is estimated on the pharmacologically induced hyperplasia of salivary glands. «Transfer-factor» sharply (11,3 times) accelerates the number of active (blast) cells of a spleen. This dietary supplement can distress thymus reaction (twenty four hours of twofold thymus atrophy) while introducing adrenostimulator. So basing on literature data and the results of our own research «Transfer-Factor» is supposed to be a perspective means of prophylaxis and correction of different pathological processes, connected with the lowered possibility of cellular self-renovation and TF can be, partly, used for the stimulation of reparative regeneration of tissues and organs. The anti-stress effect of this dietary supplement action on the immune system is interesting and also perspective.

About the authors

V I Dontsov

Moscow State Medical and Dentistry University

Национальный геронтологический центрпроспект 60-летия Октября, 9, Москва, Россия, 117312; Московский государственныймедико-стоматологический университет; Moscow State Medical and Dentistry University

V N Krutko

The Institute for the Systems Analysis of the Russian Academy of Sciences

Национальный геронтологический центрпроспект 60-летия Октября, 9, Москва, Россия, 117312; Институт системного анализа РАН; The Institute for the Systems Analysis of the Russian Academy of Sciences

A A Kudashov

OOO «VNIPIM»

OOO «VNIPIM»

M A Vanyukhina

The Institute for the Systems Analysis of the Russian Academy of Sciences

Национальный геронтологический центрпроспект 60-летия Октября, 9, Москва, Россия, 117312; Институт системного анализа РАН; The Institute for the Systems Analysis of the Russian Academy of Sciences

V A Santalova

The Peoples' Friendship University of Russia

Институт системного анализа РАН; The Peoples' Friendship University of Russia

A Ya Chizhov

The National Gerontology Center

Экологический факультетРоссийский университет дружбы народовПодольское шоссе, 8/5, Москва, Россия, 113093; Национальный геронтологический центр; The National Gerontology Center

References


Copyright (c) 2009 Dontsov V.I., Krutko V.N., Kudashov A.A., Vanyukhina M.A., Santalova V.A., Chizhov A.Y.

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