Comparative evaluation of tissue reaction to the implantation of conventional polypropylene meshes end with autofibroblasts

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Abstract


One of the possible ways to solve the problem of improving the integration of polypropylene prostheses in the tissue of the patient in the treatment of hernias of the abdominal wall is the application, making and use of composite polypropylene mesh with a coating of own fibroblasts. In the experiment on the basis of morphometric analysis a comprehensive assessment of the effectiveness of the use of covering of «heavyweight» and «lightweight» polypropylene meshes by autofibroblasts has been conducted. The use of composite mesh, consisting of the «heavyweight» or «lightweight» polypropylene mesh and autofibroblasts in all cases, allows to speak about the more pronounced proliferative process compared with the group, using only the polypropylene mesh. The ability to create a composite polypropylene mesh with fixed autofibroblasts on the basis of «lightweight» and «heavyweight» composite polypropylene meshes has been proved.

V N Egiev

Peoples’ Friendship University of Russia

Email: egiev@com2com.ru
Chair of surgery and oncology Professional Development Department of the Medical Profession

D V Chizhov

City Clinical Hospital N12

S N Shurygin

City Clinical Hospital N12

A I Shchogolev

Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare of Russian Federation

Email: ashegolev@oparina4.ru
Department Federal Budget Institution

E A Dubova

Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare of Russian Federation

Email: e_dubova@oparina4.ru
Department Federal Budget Institution

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Copyright (c) 2012 Егиев В.Н., Чижов Д.В., Шурыгин С.Н., Щеголев А.И., Дубова Е.А.

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