Diagnostic and prognostic importance of Ki-67, MMP-9 and collagen iv immunohistochemical markers in bladder tumors

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Abstract


The prognostic value of the expression Ki-67, ММР-9 and collagen IV in urotelial bladder tumors were estimated. The biopsy and surgery samples from 43patients (27males and 16 females) aged from 42 till 87 years (average age 66 ± 1,5 years) who received combined therapy for urotelial tumors were analyzed. It has been found that Ki-67, ММР-9 and collagen IV are important prognostic markers of urotelial invasive bladder carcinoma (BC).

V P Avdoshin

Peoples' Friendship University of Russia

Email: susya@kmail.ru
Кафедра урологии и оперативной нефрологии; Российский университет дружбы народов; Peoples' Friendship University of Russia

E V Kotelnikova

Peoples' Friendship University of Russia

Email: susya@kmail.ru
Кафедра урологии и оперативной нефрологии; Российский университет дружбы народов; Peoples' Friendship University of Russia

I I Babichenko

Peoples' Friendship University of Russia

Email: babichenko@med.rudn.ru <mailto:babichenko@med.rudn.ru>
Кафедра патологической анатомии; Российский университет дружбы народов; Peoples' Friendship University of Russia

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Copyright (c) 2011 Авдошин В.П., Котельникова Е.В., Бабиченко И.И.

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