Investigation of a mathematical model of a bio-artificial liver using a PID-controller

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Abstract

The objective of this study is to develop and analyze a mathematical model of a bio-artificial liver using proportional-integral-differential a controller for managing key processes. The bio-artificial liver is a complex system that performs the fundamental functions of the liver, which is of critical importance for the development of alternative treatments for patients with liver failure. The paper describes the structure and functionality of the bio-artificial liver model, based on a review of the anatomy of the human liver, as well as on the study of bio-technological aspects of the creation of artificial organs. The application of a PID-controller is considered, which allows precise and adaptive control of processes within the model, such as the supply of nutrients and the removal of toxins. The research methodology covers the creation of a mathematical model, its computer modeling and analysis of the data obtained. The experimental part of the work is to identify the optimal parameters of the PID-controller for various operating conditions of the bio-artificial liver. The results of this study can contribute to improving the effectiveness of bio-artificial systems for supporting liver functions and offer new approaches to the implementation of artificial organs, which has significant potential for the field of transplantation and treatment of liver diseases.

About the authors

Alexey S. Ganshin

RUDN University

Email: 1042210064@pfur.ru
ORCID iD: 0000-0003-3582-4889

Postgraduate student of the Department of Mechanics and Control Processes, Academy of Engineering

Moscow, Russia

Denis A. Andrikov

RUDN University

Author for correspondence.
Email: andrikovdenis@mail.ru
ORCID iD: 0000-0003-0359-0897
SPIN-code: 8247-7310

Candidate of Technical Sciences, Associate Professor of the Department of Mechanics and Control Processes, Academy of Engineering

Moscow, Russia

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Copyright (c) 2024 Ganshin A.S., Andrikov D.A.

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