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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Discrete and Continuous Models and Applied Computational Science</journal-id><journal-title-group><journal-title xml:lang="en">Discrete and Continuous Models and Applied Computational Science</journal-title><trans-title-group xml:lang="ru"><trans-title>Discrete and Continuous Models and Applied Computational Science</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2658-4670</issn><issn publication-format="electronic">2658-7149</issn><publisher><publisher-name xml:lang="en">Peoples' Friendship University of Russia named after Patrice Lumumba (RUDN University)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">45257</article-id><article-id pub-id-type="doi">10.22363/2658-4670-2025-33-2-199-213</article-id><article-id pub-id-type="edn">BOMUBB</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Modeling and Simulation</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Математическое моделирование</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Evaluating quantum-classical heuristics for traveling salesman problem</article-title><trans-title-group xml:lang="ru"><trans-title>Исследование квантово-классической эвристики для задачи коммивояжера</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7982-0209</contrib-id><contrib-id contrib-id-type="scopus">57204436887</contrib-id><contrib-id contrib-id-type="researcherid">AAZ-7810-2021</contrib-id><name-alternatives><name xml:lang="en"><surname>Makarova</surname><given-names>Mariia A.</given-names></name><name xml:lang="ru"><surname>Макарова</surname><given-names>М. А.</given-names></name></name-alternatives><bio xml:lang="en"><p>junior researcher, PhD student, SMITS Lab, Institute of Applied Mathematical Research of the Karelian Research Center of Russian Academy of Sciences; lecturer, Petrozavodsk State University</p></bio><email>masha.mariam.maltseva@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Fedorov</surname><given-names>Sergey V.</given-names></name><name xml:lang="ru"><surname>Федоров</surname><given-names>С. В.</given-names></name></name-alternatives><bio xml:lang="en">Bachelor’s degree student</bio><email>sergey-fedorov-04@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Titova</surname><given-names>Anna V.</given-names></name><name xml:lang="ru"><surname>Титова</surname><given-names>А. В.</given-names></name></name-alternatives><bio xml:lang="en">Bachelor’s degree student</bio><email>masha.mariam.maltseva@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Khomich</surname><given-names>Alexander A.</given-names></name><name xml:lang="ru"><surname>Хомич</surname><given-names>А. А.</given-names></name></name-alternatives><bio xml:lang="en">Bachelor’s degree student</bio><email>masha.mariam.maltseva@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2364-5939</contrib-id><contrib-id contrib-id-type="scopus">36968331100</contrib-id><contrib-id contrib-id-type="researcherid">L-1354-2013</contrib-id><name-alternatives><name xml:lang="en"><surname>Rumyantsev</surname><given-names>Alexander S.</given-names></name><name xml:lang="ru"><surname>Румянцев</surname><given-names>А. С.</given-names></name></name-alternatives><bio xml:lang="en"><p>Doctor of Physical and Mathematical Sciences, Leading researcher, SMITS Lab, Institute of Applied Mathematical Research of the Karelian Research Center of Russian Academy of Sciences; professor, Petrozavodsk State University</p></bio><email>ar0@krc.karelia.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Petrozavodsk State University</institution></aff><aff><institution xml:lang="ru">Петрозаводский государственный университет</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Institute of Applied Mathematical Research of the KarRC RAS</institution></aff><aff><institution xml:lang="ru">Институт прикладных математических исследований КарНЦ РАН</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-07-15" publication-format="electronic"><day>15</day><month>07</month><year>2025</year></pub-date><volume>33</volume><issue>2</issue><issue-title xml:lang="en">VOL 33, NO2 (2025)</issue-title><issue-title xml:lang="ru">ТОМ 33, №2 (2025)</issue-title><fpage>199</fpage><lpage>213</lpage><history><date date-type="received" iso-8601-date="2025-07-25"><day>25</day><month>07</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Makarova M.A., Fedorov S.V., Titova A.V., Khomich A.A., Rumyantsev A.S.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Макарова М.А., Федоров С.В., Титова А.В., Хомич А.А., Румянцев А.С.</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Makarova M.A., Fedorov S.V., Titova A.V., Khomich A.A., Rumyantsev A.S.</copyright-holder><copyright-holder xml:lang="ru">Макарова М.А., Федоров С.В., Титова А.В., Хомич А.А., Румянцев А.С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.rudn.ru/miph/article/view/45257">https://journals.rudn.ru/miph/article/view/45257</self-uri><abstract xml:lang="en"><p>In this paper, we develop and evaluate a hybrid quantum-classical heuristic approach to solving the Traveling Salesman Problem. This approach uses exhaustive enumeration of the starting paths and optimizes the remainder of the route using quantum computing. For quantum co-processing, we use either the Variational Quantum Eigensolver or the Quantum Annealing. Results of evaluation of the approach on several datasets including TSPLIB and touristic data for Petrozavodsk and Karelia Republic, both in simulation and in hardware, are presented. Issues of practical applicability are also discussed.</p></abstract><trans-abstract xml:lang="ru"><p>В статье разрабатывается и оценивается гибридный квантово-классический эвристический подход к решению задачи коммивояжера. Этот подход использует исчерпывающий перебор начальных путей и оптимизирует оставшуюся часть маршрута с помощью квантовых вычислений. Для обработки на квантовой машине используется либо вариационный квантовый собственный решатель, либо квантовый отжиг. Представлены результаты оценки предложенного подхода на нескольких наборах данных, включая TSPLIB и туристические данные для Петрозаводска и Республики Карелия, как в режиме имитации, так и на соответствующей квантовой машине. Обсуждаются вопросы практической применимости.</p></trans-abstract><kwd-group xml:lang="en"><kwd>hybrid quantum-classical heuristics</kwd><kwd>traveling salesman problem</kwd><kwd>variational quantum eigensolver</kwd><kwd>quantum annealing</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>гибридная квантово-классическая эвристика</kwd><kwd>задача коммивояжера</kwd><kwd>вариационный квантовый собственный решатель</kwd><kwd>квантовый отжиг</kwd></kwd-group><funding-group><funding-statement xml:lang="en">The research described in this publication was made possible in part by R&amp;D Support Program for undergraduate and graduate students and postdoctoral researchers of PetrSU, funded by the Government of the Republic of Karelia. Experiments were conducted with the help of high-performance computing cluster of the Center for Collective Use “High-Performance Data Center” of the Karelian Research Center of RAS.</funding-statement><funding-statement xml:lang="ru">The research described in this publication was made possible in part by R&amp;D Support Program for undergraduate and graduate students and postdoctoral researchers of PetrSU, funded by the Government of the Republic of Karelia. Experiments were conducted with the help of high-performance computing cluster of the Center for Collective Use “High-Performance Data Center” of the Karelian Research Center of RAS.</funding-statement></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Jünger, M., Reinelt, G. &amp; Rinaldi, G. 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