RUDN Journal of MedicineRUDN Journal of MedicineВестник Российского университета дружбы народов. Серия: Медицина2313-02452313-0261Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University)4681610.22363/2313-0245-2025-29-1-95-103GBJJXNPHYSIOLOGY. EXPERIMENTAL PHYSIOLOGYФИЗИОЛОГИЯ. ЭКСПЕРИМЕНТАЛЬНАЯ ФИЗИОЛОГИЯReview ArticleAutonomic functions testingТестирование автономных функцийhttps://orcid.org/0000-0002-6505-4216GuptaKapilГуптаК.sainiravi414@gmail.comhttps://orcid.org/0000-0001-8154-9385SainiRaviСаиниР.sainiravi414@gmail.comhttps://orcid.org/0009-0005-3178-6522JangidNainaДжангидН.sainiravi414@gmail.comSawai Man Singh medical collegeМедицинский колледж Савай Ман Сингх15102025291PHYSIOLOGY. EXPERIMENTAL PHYSIOLOGYФИЗИОЛОГИЯ. ЭКСПЕРИМЕНТАЛЬНАЯ ФИЗИОЛОГИЯ9510301112025Copyright ©; 2025, Gupta K., Saini R., Jangid N.Copyright ©; 2025, Гупта К., Саини Р., Джангид Н.2025Gupta K., Saini R., Jangid N.Гупта К., Саини Р., Джангид Н.https://creativecommons.org/licenses/by-nc/4.0https://journals.rudn.ru/medicine/article/view/46816

Relevance. The ubiquitous nature of the sympathetic and parasympathetic nervous system has allowed detailed tests in a variety of systems, including cardiovascular, gastrointestinal, urogenital, pupillary, sudomotor, and neuroendocrine. The most important characteristics of these tests are that they should be non-invasive, sensitive, specific, repeatable, quantitative, clinically useful and time-efficient. These tests were designed to investigate the possibility of autonomic failure, measure its severity, and assess its distribution. Clinical testing and research tests are the two main categories of these examinations. Cardiovagal, sudomotor and adrenergic autonomic functions are assessed by standard laboratory tests. The sweat test based on for measurement of the thermoregulation and the quantitative sudomotor axon reflex test (QSART) can be used to assess sudomotor function. Response of blood pressure and response of heart rate to Valsalva maneuver and head tilt are used to assess adrenal function, and extended hand grip tests are effective in determining the presence of autonomic failure, its natural history, and response to treatment. The Autonomic Function Test Battery is a set of tests for autonomous functioning. The Ewing battery is commonly used, which includes several parasympathetic and sympathetic tests. Conclusion. Autonomic function testing has a considerable amount of diagnostic importance, which can have preventive value due to a large number of mortality due to autonomic disorders.

Актуальность. Повсеместная природа симпатической и парасимпатической нервной системы позволила проводить подробные тесты в различных системах, включая сердечно-сосудистую, желудочно-кишечную, мочеполовую, зрительную, судомоторную и нейроэндокринную. Наиболее важными характеристиками этих тестов являются то, что они должны быть неинвазивными, чувствительными, специфичными, повторяемыми, количественными, клинически полезными и эффективными по времени. Эти тесты были разработаны для исследования возможности автономной недостаточности, измерения ее тяжести и оценки ее распространения. Клинические испытания и исследовательские тесты являются двумя основными категориями этих обследований. Кардиовагальные, судомоторные и адренергические автономные функции оцениваются с помощью стандартных лабораторных тестов. Тест на пот, основанный на измерении терморегуляции, и количественный тест рефлекса судомоторного аксона (QSART) можно использовать для оценки судомоторной функции. Реакция артериального давления и реакция частоты сердечных сокращений на маневр Вальсальвы и наклон головы используются для оценки функции надпочечников, а тесты с расширенным захватом руки эффективны для определения наличия автономной недостаточности, ее естественного течения и реакции на лечение. Набор тестов автономной функции представляет собой совокупность тестов для оценки автономного функционирования. Обычно используется набор Юинга, который включает несколько тестов для парасимпатической и симпатической нервной системы. Выводы . Тестирование функции вегетативной нервной системы имеет большое диагностическое значение, которое также может иметь и профилактическое значение ввиду большого количества смертей из-за расстройств вегетативных функций.

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